摘要
目的探讨降钙素原(PCT)、内毒素(ET)检测及G试验在ICU恶性肿瘤患者感染监测中的临床意义。方法纳入ICU恶性肿瘤患者158例,分为病例对照组、细菌感染组、真菌感染组,比较3组中PCT、ET检测和G试验检测的差异。结果在细菌感染组中,全身感染组、局部感染组与对照组相比,PCT、ET检测值明显升高,差异有统计学意义(P<0.01)。在真菌感染组中,浅部感染组、深部感染组与对照组相比,PCT、G试验检测值明显升高,差异有统计学意义(P<0.01)。运用平行试验,PCT、ET联合检测细菌感染和PCT、G试验联合检测真菌感染的灵敏度均升高,减少了漏诊。结论 PCT、ET及G试验定量测定具有快速、敏感的特点,合理联合测定可作为早期识别恶性肿瘤患者细菌、真菌感染及其严重性的重要指标。
Objective To investigate the clinical significance of infection surveillance about procalcitonin （PCT）,endotoxin （ET） and G test in the intensive care cancer patients. Methods We included 158 cases of ICU patients,and they were randomly di- vided into control group,bacterial infection group and fungal infection group. And we try to find the quantitative differences in the levels of proealeitonin,endotoxin and G test in these three groups. Results Compared with the control group,levels of PCT and ET were significantly increased in systemic infection group and local infection group（P〈0.01） ;compared with the control group,PCT and G test results were significantly increased in superficial infection and deep infection group （P〈0. 01）. Using the parallel test from detection of PCT,ET and G test,the sensitivity of bacterial infection and fungal infection are rising, thereby it will reduce the misdiagnosis. Conclusion Detecting PCT,endotoxin and G test is rapid and Sensitive. They could act as indicator for early identifi- cation of bacterial ,fungal infections and severity of the infection. [Key words] endotoxins; procalcitonin;G test;malignant tumor
出处
《重庆医学》
CAS
北大核心
2015年第21期2944-2946,共3页
Chongqing medicine
