摘要
肝门胆管癌(hilar cholangiocarcinoma,HCCA)是指发生在左、右肝管及肝总管的恶性肿瘤,是最常见的胆管癌.因其早期发病隐匿,临床症状出现较晚,多数患者诊断时往往处于中晚期阶段,导致手术难度及风险大,预后较差.近年来,随着影像学技术的发展、扩大根治术式的广泛开展,对于HCCA的术前诊断及手术疗效得到逐渐提高.但是,HCCA根治率低、并发症多、预后不良等问题仍然很严峻,我们应加强对HCCA的易感因素及生物学特性的研究,力争早期诊断.判断肿瘤能否切除尚无统一标准,对无明显禁忌证的确诊病例应积极手术,力争通过联合部分肝切除根治HCCA.本文就HCCA的外科手术及相关问题的研究进展作一综述.
Hilar cholangiocarcinoma,a malignant tumor that occurs in the left and right hepatic duct,is the most common form of bile duct carcinoma.Early diagnosis of hilar cholangiocarcinoma is difficult,and the majority of patients are diagnosed in advanced stages.Therefore,surgery for this malignancy is difficult,has high risk,and is associated with a poor prognosis.In recent years,with the development of imaging technology and extended radical surgery,the preoperative diagnosis and surgical treatment of hilar cholangiocarcinoma have been improved.However,hilar cholangiocarcinoma still has a low cure rate,high complication rate,and poor prognosis.Therefore,we should strengthen the research on the susceptible factors and biological characteristics of hilar cholangiocarcinoma,and improve early diagnosis.Currently,although there has been no unified standard for the resectability of the tumor,surgery combined with partial hepatectomy is strongly recommended in patients without surgical contraindication.This paper reviews the recent progress in surgical treatment of hilar cholangiocarcinoma.
出处
《世界华人消化杂志》
CAS
2015年第18期2907-2912,共6页
World Chinese Journal of Digestology
关键词
肝门胆管癌
分型
胆道引流
门静脉栓塞
外科手术
肝叶切除
Hilar cholangiocarcinoma
Classification
Biliary drainage
Portal vein embolization
Surgery
Hepatectomy
