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羟考酮或芬太尼预给药对依托咪酯所致肌阵挛的影响 被引量:11

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摘要 有报道静注依托咪酯后肌阵挛的发生率可高达50%-80%[1]。芬太尼常用于预防依托咪酯所致肌阵挛。但不良反应明显,如呼吸抑制[2]。羟考酮除作用于μ受体还激动κ受体,其镇痛效能好,但目前对羟考酮预防依托咪酯导致的肌阵挛尚无文献报道。本文为前瞻性,随机双盲对照研究,并对羟考酮的不良反应进行观察,为临床预防依托咪酯所致的肌阵挛提供参考。
出处 《临床麻醉学杂志》 CAS CSCD 北大核心 2015年第7期707-708,共2页 Journal of Clinical Anesthesiology
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