摘要
应用国产头孢三嗪治疗临床各类感染82例,包括呼吸系统感染、腹腔感染、伤寒、败血症、宫腔感染、尿路感染和急性淋病。大多数患者具有严重原发疾病,部分患者为医院内感染和免疫缺陷者感染,经头孢三嗪治疗后总有效率为91.5％,细菌清除率为87.7％。临床应用中不良反应轻微,不良反应发生率为6.1％。头孢三嗪和哌拉西林联合庆大霉素随机对照治疗呼吸系统和腹腔感染共55例,头孢三嗪组有效率(93.3％)高于对照组(68％)(P<0.05)。两组不良反应发生率的差别无显著意义。
Ceftriaxone was used for the treatment of 82 patients, including pulmonary infections, intraabdominal infections,typhoid fever, septicemia , endometritis or pelvic infections, urinary tract infections and uncomplicated gonorrhoea etc. The total effective rate was 91.5%, the cure rate being 68.3% and the bacteria clearance rate being 87.7%.Most of these patients have severe underlying diseases and some were nosocomial infections or compromised hosts. Most patients responded favourably. The adverse reactions were rare and mild. The randomised comparative study of ceftriaxone vs piperacillin plus gentamicin to treat pulmonary infections and intraabdominal infections showed that the effective rate of ceftriaxone (93.3%)was higher than that of piperacllin plus gentamicin(68%)(p<0.05). The adverse reaction rate in two groups did not differ significantly.
出处
《中国抗生素杂志》
CAS
CSCD
北大核心
1991年第6期442-446,共5页
Chinese Journal of Antibiotics
关键词
头孢三嗪
感染
抗生素
Ceftriaxone
Bacterial infection
Randpazised comparative study
