摘要
目的：对两种淋巴结清扫方式用于早期肺癌治疗中对患者预后的影响进行比较，为临床治疗提供指导。方法选取采用择期手术治疗的早期肺癌患者98例为研究对象，按照随机数字表法将其分为两组，每组49例。排序为奇数的患者为观察组，予以系统性淋巴结清扫（LND）；排序为偶数的患者为对照组，予以系统性采样淋巴结清扫（LNS）。对术后淋巴清扫手术相关数据进行分析，对两组5年生存率、复发率、生存质量等数据进行比较及统计学分析。结果观察组淋巴清扫个数，手术时间，3年、5年生存率，2年、3年、5年复发率及生存质量总评分均优于对照组，且差异均有统计学意义（均 P ＜0．05）；出血量、3个月和2年生存率、生存质量各单项评分等数据比较，两组差异均无统计学意义（均 P ＞0．05）；观察组神经损伤率高于对照组，差异有统计学意义（P ＜0．05）。结论LND 用于早期肺癌的治疗中具有清扫彻底、手术时间短、短期生存率高、复发率低、生存质量高等优势，具有推广价值。但存在出血量多、神经损伤率高等缺陷，仍需进一步完善。
Objective To investigate two kinds of methods of lymph node dissection for early effects on the prognosis of the patients in the treatment of lung cancer by comparative study,and provide guidance for clinical treat-ment.Methods 98 cases of early stage lung cancer patients who were taken using elective surgery were selected in the study.According to the random number table,they were divided into two groups of 49 cases for each other.Sort of an odd number of patients in the observation group,and given systematic lymph node dissection （LND）;sort of an even number of patients in the control group,which was systematically sampled lymph node dissection （LNS）.After dissection from the relevant data,following -up of 5 -year survival,relapse rate,quality of life and other data for com-parison and statistical analysis were accessed.Results In the observation group,the number of lymphatic vessels in the cleaning,operation time,3 years,the survival rate of 5 years,2 years,3 years and 5 years recurrence rate and survival quality total score comparison is superior to the control group,with significant difference （P 〈0.05）;The amount of bleeding,3 months and 2 years the survival rate,quality of life of each individual score data comparison of the two groups had no significant differences （all P 〉0.05）;The nerve injury rate of the observation group was higher than the control group,there was significant difference （P 〈0.05）.Conclusion Systematic lymph node dissection for treatment of early lung cancer has a thorough cleaning,operation time is short,the short -term survival rate is high,low recurrence rate,high quality of life and other advantages,and has the value of popularization.But there was the amount of bleeding,nerve injury and high rate of defects,it needs to be further perfected.
出处
《中国基层医药》
CAS
2015年第13期2037-2040,共4页
Chinese Journal of Primary Medicine and Pharmacy
关键词
肺肿瘤
淋巴结清扫术
生存质量
神经损伤
Lung neoplasms
Lymph node dissection
Quality of life
Nerve injury
