摘要
目的研究MRI诊断新生儿低血糖脑病的临床价值及影像学特征。方法选取2012年1月~2014年1月收治的42例新生儿低血糖脑损伤患儿（脑损组）,并与同期就诊的45例新生儿低血糖无脑损伤患儿（对照组）进行MRI检查,以临床治疗及其他多种影像学综合诊断作为金标准,分析MRI诊断新生儿低血糖脑损伤的临床价值和MRI特征。结果脑损组血糖最低值显著低于对照组,低血糖持续时间显著长于对照组,治疗24h、48h时血糖水平显著低于对照组,差异均有统计学意义（P〈0.05）;MRI诊断新生儿低血糖脑病灵敏度为92.9%（39/42）,特异度为88.9%（40/45）,准确度为91.0%（79/87）。结论新生儿低血糖脑损伤患儿一般双侧枕顶叶后部以及胼胝体受损严重,且常呈对称性分布,MRI在对新生儿低血糖脑损伤的评估上准确性较高,对新生儿低血糖脑病患儿的治疗以及预后判断均有重要的临床指导意义。
Objective To study the clinical value and imaging features of MRI in the diagnosis of neonatal hypoglycemia encephalopathy.Methods 42 children with neonatal hypoglycemic brain injury was selected as brain damage group.45 cases of neonatal hypoglycemia without brain injury during the same period were selected as control group.The patients in both groups were underwent MRI detection.The clinical value and imaging features of MRI in the diagnosis of neonatal hypoglycemia encephalopathy was analyzed according to gold standard of clinical treatment and other integrated imaging diagnostics.Results The lowest blood glucose levels of brain damage group was significantly lower than that of control group.The duration of hypoglycemia of brain damage group was significantly longer than control group.The blood gloucose levels of brain damage group underwent 24 hours and 48 hours treatment were significantly lower than control group（P〈0.05）.The sensitivity,specificity and accuracy of MRI in the diagnosis of neonatal hypoglycemia encephalopathy were 92.9%（39/42）,88.9%（40/45）and 91.0%（79/87）,respectively.Conclusion The back of bilateral occipital parietal lobe and the corpus callosum of children with neonatal hypoglycemic brain injury are usually severely damaged and often show symmetrical distribution,MRI in the assessment of neonatal hypoglycemic brain injury has higher accuracy and has important guiding significance in the treatment and prognosis judgment of neonatal hypoglycemic.
出处
《西部医学》
2015年第7期1065-1068,共4页
Medical Journal of West China
基金
国家自然科学基金(1001420764)
四川省凉山州卫生局科研课题(14YYJS0009)
关键词
新生儿
低血糖
脑病
MRI
影像学
Neonatal
Hypoglycemia
Encephalopathy
MRI
Imaging
