摘要
目的探讨急性腹泻病患儿血锌变化及口服赖氨葡锌颗粒对婴幼儿急性腹泻病的治疗和预防效果。方法将118例急性腹泻病患儿随机分为治疗组58例,对照组60例,两组均采用综合治疗,治疗组加用赖氨葡锌颗粒治疗。观察两组患儿在治疗期间的临床症状消失时间,比较两组治疗效果;对所有病例均在治疗后1、2、3个月各随访1次,观察两组患儿在此期间再次出现腹泻的发病率,出现腹泻时病情的严重程度。结果治疗组各临床症状消失时间较对照组明显缩短,差异有显著性(P<0.01);治疗组的总有效率明显高于对照组(P<0.05);随访3个月后,治疗组的腹泻再发生率明显低于对照组(P<0.05)。结论急性腹泻患儿均明显存在锌缺乏,口服赖氨葡锌颗粒有助于急性腹泻病的防治。
Objective To investigate serum zinc level in infant with acute diarrhea and the therapy and prevention effect of compound iysine hydrochloride and zinc gluconate granules（CLHZGG）on infant with acute diarrhea.MethodsSerum zinc level from 184 infant with acute diarrhea were tested and contrasted with that in health infant.This was a single-blind randomized control clinical study.118 patients with acute diarrhea were divided randomly into two groups,58 cases in treatment group and 60 cases in contrast group.These two groups all treated with combined therapy,and treatment group still given CLHZGG.The symptom remission time was recorded,and the therapeutic effect between two groups was compared.These patients were followed up in 1,2,3months after treatment,and investigated the morbidity of diarrhea again and the disease severity when have diarrhea.Results The symptom remission times in treatment group were significantly shorter than those of contrast group.The total effect rate in treatment group was significantly higher than this of contrast group.During more than 3 months follow-up,the morbidity of diarrhea again in treatment group was significantly lower than this of contrast group.Conclusion Element zinc was deficiency in infant with acute diarrhea,and CLHZGG will helpful to prevention and cure of acute diarrhea.
出处
《西部医学》
2015年第7期1040-1041,1045,共3页
Medical Journal of West China
基金
南充市应用技术与研究开发项目(12A0039)
关键词
急性腹泻
婴幼儿
锌
治疗
预防
Acute diarrhea
Infant
Zinc
Treatment
Prevention
