摘要
目的观察乌司他丁联合早期血液灌流与仅给予早期血液灌流治疗急性重症胰腺炎的临床效果。方法随机选取收治的102例急性重症胰腺炎患者,根据治疗方法不同随机分为研究组和对照组,其中研究组52例,给予乌司他丁联合早期血液灌流治疗;对照组50例,只给予早期血液灌流治疗,观察两组患者临床治疗效果。结果两组患者腹胀消失时间、腹痛消失时间、WBC恢复时间、血清淀粉酶恢复时间、尿淀粉酶恢复时间和住院时间比较,研究组均明显少于对照组,差异有统计学意义(P<0.05)。临床治疗总有效率研究组明显高于对照组,差异有统计学意义(P<0.05)。两组不良反应发生率研究组明显低于对照组,差异有统计学意义(P<0.05)。结论乌司他丁联合早期血液灌流治疗急性重症胰腺炎能明显改善临床症状和提高治疗效果,且不良反应少,可在临床推广应用。
Objective To observe and analyze the clinical effect of ulinastain combined with early hemoperfusion in treatment of acute severe pancreatitis.Method 102 patients with acute severe pancreatitis were selected in this study.According to different treatments,the participants are divided into the research group and the control group.In this research,there were 52 participants in the research group,who were treated by ulinastain combined with early hemoperfusion.There were 50 participants in the control group,who were treated only by early hemoperfusion.We analyzed the clinical effect.Result The abdominal distention disappear time,abdominal pain disappear time,hospitalization time and its＇ recovery time of WBC,recovery time of serum and urine amylase of research group were shorter than that of the control group（P〈0.05）.The research group＇s efficiency of clinical curative effect was higher than the control group（P〈0.05）.The research group＇s incidence of adverse reaction was less than the control group（P〈0.05）.Conclusion It is effective to treat acute severe pancreatitis with ulinastain combined with early hemoperfusion.
出处
《西部医学》
2015年第7期1028-1030,共3页
Medical Journal of West China
基金
成都市科技研究项目(9512011Y0413)
