摘要
目的探讨贝复济(碱性成纤维化细胞生长因子,BFGF)联合封闭式负压引流对于普外科难愈性伤口的临床疗效。方法随机将100例普外科手术后难愈性伤口患者平均分为两组,即封闭式负压引流治疗组(对照组)和贝复济联合封闭式负压引流治疗组(观察组),每组50例。对治疗有效率、换药次数、伤口愈合时间及患者住院时间进行分析。结果观察组治疗的临床有效率、换药次数、伤口愈合时间及患者住院时间均显著优于对照组,差异均有统计学意义(P<0.05)。结论在封闭式负压引流(VSD)的基础上使用碱性成纤维化细胞生长因子对于普外科手术导致的难愈性伤口有较好的临床疗效,可在临床推广应用。
Objective To explore the effect of bFGF combined with vacuum sealing drainage（VSD）in treatment of abdominal surgery induced refractory wounds.Methods 100 patients with abdominal surgery induced refractory wounds were randomly divided into vacuum sealing drainage treatment group（control group）and bFGF ＋ vacuum sealing drainage treatment group（observe group）.The effective power,frequency of dressings change,healing time and length of stay were analyzed.Results The effective power,frequency of dressings change,healing time and length of stay in observe group were all better than that in control group（P〈0.05）.Conclusion Our results showed that bFGF combined with vacuum sealing drainage（VSD）was an effective and safe methods for the treatment of abdominal surgery induced refractory wounds.
出处
《西部医学》
2015年第7期1019-1021,共3页
Medical Journal of West China
基金
四川省教育厅科研课题(11ZB172)
