摘要
目的探讨术前心肺运动训练对肺癌合并慢性阻塞性肺疾病(COPD)患者围术期心肺功能及术后并发症的影响。方法选取98例拟行肺癌切除术且合并COPD的肺癌患者,随机分为观察组和对照组各49例,两组术前均给予改善肺功能治疗,观察组同时行心肺运动训练2周。比较两组术前1天静态肺功能[用力肺活量(FVC)、1秒用力呼气容积、最大自主通气量(MVV)、一氧化碳弥散总量(DLCO)及术后预计FEV1]运动心肺功能[最大摄氧量(VO2max)、公斤摄氧量(VO2/kg)、无氧阈(AT)、氧脉搏(O2pulse)、最大心率、最大分钟通气量(VEmax)及呼吸困难指数]的变化。比较两组术后并发症、氧疗时间、机械通气时间和住院时间。结果观察组FVC、MVV、DLCO、VO2max、VO2/kg、AT、O2pulse、VEmax较对照组均有不同程度的改善(P均<0.05);两组术后总体心肺并发症及单个并发症的发生率、术后氧疗时间、机械通气时间及住院天数比较差异均有统计学意义(P均<0.05)。结论术前心肺运动训练能明显改善肺癌合并COPD患者的心肺功能,减少术后并发症、缩短住院时间,利于患者早日康复。
Objective To investigate the effect of preoperatively cardiopulmonary exercise training on the cardiopul -monary function and postoperative complications in lung cancer patients with chronic obstructive pulmonary disease （ COPD） .Methods Ninety-eight lung cancer patients with COPD who would receive lung cancer resection were randomly divided into two groups：the observation group and the control group , 49 cases in each group .Both groups were treated to improve the lung function before surgery , and the observation group was treated with cardiopulmonary exercise training for two weeks .The indicators of static lung function and dynamic cardiopulmonary exercise were compared between the two groups the day before surgery .The differences of postoperative complications , duration of oxygen therapy , mechanical ven-tilation and length of hospital stay were compared between the two groups .Results In the observation group , FVC, MVV, DL CO, VO2 max, VO2/kg, AT, O2 pulse and VEmax were improved to varying degrees as compared with those in the con-trol group （all P〈0.05）.Significant differences were found in the incidences of the overall postoperative cardiopulmonary complications and individual complications , the time of postoperative oxygen therapy , mechanical ventilation and length of hospital stay between the two groups （all P〈0.05）.Conclusions Preoperative cardiopulmonary exercise training can im-prove heart and lung functions in the lung cancer patients with COPD .Meanwhile , it may reduce postoperative complica-tions, shorten the hospital stay and help the patients to recover soon .
出处
《山东医药》
CAS
北大核心
2015年第18期21-23,共3页
Shandong Medical Journal
关键词
慢性阻塞性肺疾病
肺癌
心肺运动训练
围手术期
chronic obstructive pulmonary disease
lung carcinoma
cardiopulmonary exercise training
perioperative period
