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氧氟沙星与盐酸左氧氟沙星治疗盆腔炎的临床疗效对比 被引量:17

Clinical efficacy of ofloxacin and levofloxacin treatment on pelvic inflammatory disease
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摘要 目的:分析并探讨盐酸左氧氟沙星治疗盆腔炎的临床疗效。方法:选取2011年7月至2014年7月在我院接受治疗的盆腔炎患者140例,随机分为观察组与对照组,每组70例。两组患者均给予常规的支持治疗,在此基础上,观察组给予盐酸左氧氟沙星治疗,对照组给予氧氟沙星治疗。结果:观察组治疗有效率为92.86%,对照组治疗有效率为80.00%。观察组治疗有效率明显高于对照组,经统计学检验,差异具有统计学意义(P<0.05)。治疗后,观察组仍有腹痛3例,子宫及附件压痛16例,盆腔积液6例,白带增多11例;对照组腹痛17例,子宫及附件压痛34例,盆腔积液16例,白带增多25例。观察组临床症状患者明显少于对照组,经统计学检验,差异具有统计学意义(P<0.05)。观察组不良反应发生率为4.29%,对照组不良反应发生率为15.71%。观察组不良反应发生率明显低于对照组,经统计学检验,差异有统计学意义(P<0.05)。结论:盐酸左氧氟沙星治疗盆腔炎临床效果显著,且不良反应发生率低,值得临床推广。 Objectives: To analyze and discuss the clinical efficacy of levofloxacin hydrochloride treatment on pelvic inflammatory disease. Methods: 140 patients with pelvic inflammatory disease treated in our hospital from July 2011 to July 2014 were randomly divided into observation group and control group, 70 cases in each group. On the basis of conventional supportive care for all the patients, observation group were given levofloxacin hydrochloride therapy, and the control group received offloading treatment. Results: The effective rate of observation group and control group were 92.86% and 80.00% respectively, with statistically significant difference ( P 〈 0.05 ). After treatment, there were 3 cases of abdominal pain, 16 cases of uterine and anneal tenderness, 6 cases of pelvic fluid in the observation group and 11 cases had increased vaginal discharge; in control group, there were 17 cases of ab- dominal pain, 34 cases of uterine and anneal tenderness, 16 cases of pelvic fluid and 25 cases had increased vaginal discharge. Clinical symptoms in observation group were significantly less than that in the control group, with statisti- cally significant difference ( P 〈 0.05 ). The adverse reaction rate of observation group and control group were 4. 29% and 15.71% respectively, with statistically significant difference ( P 〈 0. 05 ). Conclusion: Levofloxacin hydrochloride has significant clinical effect on the treatment of pelvic inflammatory disease with low incidence of ad- verse reactions, which is worthy of promotion.
作者 金敏丽 张丹
出处 《中国性科学》 2015年第6期11-13,共3页 Chinese Journal of Human Sexuality
关键词 盐酸左氧氟沙星 盆腔炎 临床疗效 不良反应 Levofloxacin hydrochloride Pelvic inflammatory disease Clinical efficacy Adverse re-actions
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