摘要
目的：探讨氯米芬联合二甲双胍治疗多囊卵巢综合征的效果。方法选取2011年2月~2014年2月本院收治的60例多囊卵巢综合征患者作为研究对象，随机分为观察组和对照组。观察组给予二甲双胍和氯米芬治疗，对照组给予氯米芬治疗。比较两组的血清雌二醇、黄体生成素、睾酮水平，并观察两组的妊娠情况。结果观察组的血清雌二醇水平显著低于对照组，差异有统计学意义（P〈0.05）。观察组的成熟卵泡数显著低于对照组，差异有统计学意义（P〈0.05）。观察组的妊娠率显著高于对照组，差异有统计学意义（P〈0.05）。结论氯米芬联合二甲双胍治疗多囊卵巢综合征效果显著，能够改善患者的排卵状况，提高妊娠率。
Objective To explore the effect of clomiphene combined with metformin in the treatment of polycystic ovary syndrome. Methods 60 cases with polycystic ovary syndrome from February 2011 to February 2014 in our hospital were selected and randomly divided into the observation group and the control group.The observation group was given metformin and clomiphene,the control group was given clomiphene.The level of serum estradiol,luteinizing hormone, testosterone in two groups was compared.The rate of pregnancy in two groups was observed. Results The level of serum estradiol in the observation group was lower than that in the control group,with significant difference （P〈0.05）.the num-ber of mature follicles in the observation group was lower than that in the control group,with significant difference （P〈0.05）.The pregnancy rate in the observation group was higher than that in the control group,with significant difference （P〈0.05）. Conclusion The effect of clomiphene combined with metformin in the treatment of polycystic ovary syndrome is significant,which can improve the ovulation in the patients with polycystic ovary syndrome ovulation,and improve the pregnancy rate.
出处
《中国当代医药》
2015年第16期127-128,131,共3页
China Modern Medicine
