摘要
黄连为我国传统中药,现代研究发现黄连具有多种药理作用。黄连具有抗氧化作用,可能通过清除氧自由基、减轻脂质过氧化反应、增强抗氧化酶活性等途径对抗高糖诱导的氧化应激损伤,同时可以抑制糖尿病多个经典病理途径的损伤,对于防治糖尿病及慢性并发症具有良好的应用前景。该文对黄连及其主要成分的抗氧化作用与糖尿病的相关研究进展进行综述。
Coptis chinensis,a traditional Chinese medicine, has been found to have multiple pharmacological effects recently. Some research showed that C. chinensis has antioxidant effects, including scavenging oxygen free radicals, alleviating lipid peroxidation, enhancing activity of antioxidant enzymes, et al. C. chinensis may inhibit several classical pathological pathways in diabetes. C. chinensis is a potential medicine to prevent and treat diabetes mellitus and its complications. This review focuses on the recent research progress in the study of antioxidant effects of C. chinensis and its major contributions to diabetes treatment/therapy.
出处
《中国中药杂志》
CAS
CSCD
北大核心
2015年第12期2285-2288,共4页
China Journal of Chinese Materia Medica
关键词
黄连
黄连素
抗氧化
氧化应激
糖尿病
Coptis chinensis
berberine
antioxidant
oxidative stress
diabetes
