摘要
目的:对胃平坦型病变进行富士能智能分光染色内镜(Fujinon intelligent chromoendoscopy,FICE)放大内镜观察,对比FICE放大内镜与病理检查的一致性,探讨FICE放大内镜在胃平坦型病变诊断中的应用价值.方法:2012-09/2014-08对江汉大学附属医院发现的248个胃黏膜平坦性病变进行富士能FICE放大内镜检查.在FICE及放大模式观察病灶腺管开口与毛细血管形态,对其形态进行分型,并结合整体内镜下表现预测病理诊断.将FICE放大内镜下的内镜判定结果与病理组织学结果进行对比,评价其一致性与关联性.FICE内镜与病理诊断的一致性评价采用Kappa检验.结果:萎缩在FICE内镜下主要表现为C、D、E型胃小凹形态;肠上皮化生在F I C E内镜下主要表现为D、E型胃小凹形态;高级别上皮内瘤变及早期癌在FICE内镜下主要表现为E、F型胃小凹形态.FICE放大内镜技术判定萎缩、肠上皮化生、异型增生及早期癌的结果与病理诊断的结果具有较好的一致性.结论:FICE放大内镜技术有助于对病变性质如炎症、萎缩、肠上皮化生、上皮内瘤变及早期癌等的判断,有较好的临床应用价值.
AIM： To explore the value of magnifying endoscopy combined with Fujinon intelligent chromoendoscopy （FICE） in the diagnosis of flat gastric lesions. METHODS： From September 2013 to August 2014, 248 patients with fiat gastric lesions who underwent magnifying endoscopy combined with FICE were included. Pit patterns and capillary morphology were observed and typed to predict pathological outcome, and the results were compared with histological results to evaluate the consistency and relevance. RESULTS： Gastric atrophy was mainly classified by FICE as types C, D, and E gastric pits patterns; intestinal metaplasia mainly as types D and E pits; high-grade intraepithelial neoplasia and early gastric cancer mainly as types E and F gastric pits. Magnifying endoscopy combined with FICE had good consistency with histology in the diagnosis of atrophy, intestinal metaplasia, high-grade intraepithelial neoplasia and early gastric cancer. CONCLUSION： Magnifying endoscopy combined with FICE can accurately diagnose gastric atrophy, intestinal metaplasia, intraepithelial neoplasia and early cancer.
出处
《世界华人消化杂志》
CAS
2015年第12期1956-1962,共7页
World Chinese Journal of Digestology
关键词
智能分光染色技术
胃平坦型病变
癌前病变
胃癌
内镜诊断
Fujinon intelligent chromoendoscopy
Flat gastric lesions
Precancerous lesions
Gastriccancer
Endoscopic diagnosis
