摘要
目的:观察比较瑞芬太尼与芬太尼两种麻醉药应用在老年患者手术中的效果。方法:选择本院2011年6月-2013年12月住院治疗的76例老年患者,并按照随机数字法分为观察组38例和对照组38例,其中观察组患者采用瑞芬太尼静脉麻醉,对照组患者采用芬太尼静脉麻醉,对比分析两组患者的麻醉效果。结果:观察组和对照组患者分别进行麻醉诱导后,其血压和心率均低于麻醉诱导前。观察组患者在插管后和切皮时无血压及心率升高现象,拔管时出现血压和心率比诱导后和手术结束时升高;对照组患者在插管后和切皮时血压及心率均出现明显升高,拔管时的血压和心率与诱导后和手术结束时相比,无明显变化。观察组患者与对照组患者相比,其自主呼吸恢复时间、拔管时间以及出麻醉室的时间都要低于对照组时间,两组比较差异具有统计学意义(P<0.05)。结论:瑞芬太尼与芬太尼在用于老年患者手术麻醉时,瑞芬太尼的麻醉效果明显要优于较芬太尼,而且瑞芬太尼对患者身体影响较小,得到临床推广。
Objective：To observe the effect of remifentanil and fentanyl two kinds of anesthesia in elderly patients in operation. Method：To select randomly 76 elderly patients in our hospital in 2012 June-2013 April during the period of hospitalization,and randomly divide them into the observation group（38 cases）and control group（38 cases）, the observation group with remifentanil intravenous anesthesia,the control group were treated by fentanyl intravenous anesthesia. To comparatively analyze anesthesia effect of two groups of patients. Result：The observation group and the control group patients were performed after induction of anesthesia,the blood pressure and heart rate were lower than those before anesthesia induction. The blood pressure and heart rate of the patients in observation group did not increase after intubation and skin incision,but increased after induction. The blood pressure and heart rate of the patients in control group increased after intubation and skin incision,but it was compared with the end of extubation,the change was not significant. Patients in the observation group compared with the control group of patients,the spontaneous breathing recovery time and extubation time and anesthesia room time was lower than that in the control group,the difference was significant（P〈0.05）. Conclusion：Remifentanil and fentanyl for anesthesia in elderly patients during the operation,the anesthetic effect of remifentanil is evidently better than fentanyl and remifentanil,less impact on the patient’s body,get the clinical promotion.
出处
《中国医学创新》
CAS
2015年第13期77-79,共3页
Medical Innovation of China
关键词
瑞芬太尼
芬太尼
老年患者
麻醉
Remifentanil
Fentanyl
Elderly patient
Anesthesia
