摘要
目的探讨超声引导下将中期多胎妊娠减至双胎的安全性,以检验该方法的可行性。资料与方法 43例接受胚胎移植的孕妇按照是否行减胎术分为:减胎组16例,于妊娠中期在超声引导下行减胎术、将多胎妊娠减至双胎;非减胎组27例,为双胎妊娠孕妇。比较两组孕妇妊娠结局的差异。结果减胎组中,1例疑似宫内感染流产,1例已分娩者于减胎后2 d内保留胎儿之一死亡,其余14例已分娩8例,6例仍在妊娠中;截止至2014年6月11日共获得17名新生儿,无新生儿死亡及畸形。非减胎组中,1例自然流产,2例已分娩者出现双胎之一停育,其余24例全部分娩;共获得50名新生儿,新生儿畸形3名,无新生儿死亡。两组在出生孕周、新生儿体重、母婴并发症等方面差异均无统计学意义(P>0.05)。结论将多胎减至双胎改善了妊娠结局,与未减胎双胎相比,两者妊娠结局无显著差异,可以认为妊娠中期将多胎减至双胎安全可行。
PurposeTo evaluate the safety and feasibility of transabdominal ultrasound guided multifetal pregnancy reduction performed in the second trimester.Materials and Methods Forty-three women receiving embryo implantation were divided into two groups according to whether they have received multifetal pregnancy reduction including 16 in the reduction group in the second trimester to reduce multiple fetuses to twins, and 27 with twin pregnancy and no reduction. The pregnancy outcome was compared.Results In the reduction group, 1 patient had miscarriage because of intrauterine infection; 1 patient lost one of the retained fetuses in two days after reduction and delivered the remaining fetus. In the other 14 cases, 8 delivered and 6 were still in pregnancy. This group had 17 newborns, all without neonatal death or birth defects. In the non-reduction group, there was 1 spontaneous abortion. In 2 patients, 1 of the twin embryos stopped development. 1 case had a spontaneous abortion, the other 24 cases delivered uneventfully. There were 50 newborns in this group with 3 birth defects and no neonatal death. There was no statistically significant difference in gestational age at delivery, birth weight, and the incidence of maternal and neonate complications （P〉0.05）.Conclusion Multifetal reduction improves pregnancy outcomes, similar to non-reduction twin pregnancy. It is safe and feasible to perform multifetal pregnancy reduction in the second trimester.
出处
《中国医学影像学杂志》
CSCD
北大核心
2015年第3期222-225,共4页
Chinese Journal of Medical Imaging
关键词
妊娠减少
多胎
超声检查
产前
超声引导
Pregnancy reduction, multifetal
Ultrasonography, prenatal： Ultrasoundguided
