摘要
近年来幽门螺杆菌(H.pylori)感染人群与日俱增,且复治者越来越多,第一次彻底根除已远远达不到临床期望水平,其主要原因是耐药菌株的产生,所以寻找更为有效的根除方案刻不容缓。新出现的方案如序贯疗法、含铋剂四联疗法、伴同疗法及混合疗法研究表明均优于标准三联,可替代其作为一线方案。以喹诺酮类为基础的疗法、以呋喃唑酮为基础的疗法、利福布丁及利福昔明可作为补救方案。益生菌及中草药也可作为辅助治疗方法,以提高H.pylori根除率。本文就上述方案研究进展作一概述。
In recent years, more and more people have helicobacter pylori （H.pylori） infection and the recurrence people are more and more , the first time eradication has far less than clinical expectation level ,the main reason is the production of drug resistant strains ,so it is very urgent to look for more effective eradication programs .The emergence of new solutions such as sequential therapy , containing bismuth agent quadruple therapy , accompany therapy and mixed therapy study are better than the standard triple ,alternative as a line .Quinolone based therapy ,furazolidone based thera-py,rifabutin and rifaximin can be used as a remedy .Probiotics and Chinese herbal medicine can also be as adjuvant ther-apy to improve H.pylori eradicate rate .In this paper ,the scheme was summarized .
出处
《胃肠病学和肝病学杂志》
CAS
2015年第4期480-483,共4页
Chinese Journal of Gastroenterology and Hepatology
关键词
幽门螺杆菌
一线治疗
补救治疗
辅助治疗
Helicobacter pylori
First-line therapy
Remedial therapy
Adjuvant therapy
