摘要
目的了解泌尿系感染假丝酵母菌菌株分布及耐药现状，为临床合理选择抗菌药物提供依据。方法回顾性调查2011年10月～2013年12月本院住院患者泌尿系发生假丝酵母菌感染的相关资料及药敏结果。结果从送检的1688份泌尿系感染患者的尿培养标本中共分离268株假丝酵母菌，检出率为15．87％，菌种以热带假丝酵母菌为主，占52．6％，其次为白色假丝酵母菌61株，占22．76％，克柔假丝酵母菌26株，占9．70％，光滑假丝酵母菌为19株，占7．09％。所有菌株体外药敏实验对两性曲霉B100％敏感，对5-氟胞嘧啶、氟康唑、伊曲康唑、酮康唑的耐药率分别是38．43％、76．49％、73．88％、74．25％。结论假丝酵母菌是泌尿系发生感染最常见的真菌，耐药性有增长趋势，应对分离菌株进行药敏试验，根据实验室的药敏试验结果指导临床合理。
Objectives To investigate the clinical character and drug resistance of Candida albicans in uri- nary tract infection, and to provide recommodation for reasonable selection of antibiotics. Methods The related clinical datas, including drug sensitivity tests of Candida albicans infection in hospitalized urinary tract infection from Januany 2011 to December 2013 ,were analyzed retrospectively. Results A total of 268 strains of Candida albi- cans were isoloted from 1688 samples of urine culture form urinary tract infection patients specimen, accounted for 15. 87%, most of Candida tropicalis them were （52.6%）, Candida albicans was 61 strais （22.76%）, candida krysei was 26 strais （9.70%） , candida glabrata was 19 strais （7.09%） , All Candida albicans strains revealed a highest susceptibility rate to amphoterien B according to drug sensitivity tests invitro. The drug resistant rate to 5 - fluorocy- tosine,fluconazole,ITC caconazole were 38.43% ,76.49% ,73.88% ,74.25%. Conclusions Candida albicans is one of the most common pathogens proceed from urinary tract infection and should be further detected and its results will guide us to use drugs appropriately and prevent infection effectively in Clinic practice.
出处
《国际泌尿系统杂志》
2015年第3期344-346,共3页
International Journal of Urology and Nephrology
关键词
泌尿道感染
酵母菌
抗药性
微生物
Urinary Tract Infections
Yeasts
Drug Resistance, Microbial
