摘要
目的 探讨胃肠道肿瘤患者采用腹腔热灌注化疗治疗的临床效果.方法 将本组纳入的85例患者根据随机数字表法随机分为观察组（n=43）和对照组（n=42）.对照组单纯采用静脉化疗治疗,观察组在对照组基础上结合腹腔热灌注治疗.对比分析两组疗效、生存质量及毒副反应发生情况.结果 观察组总有效率明显高于对照组（65.12％ vs.40.48％,P＜0.05）;观察组生存质量改善率显著高于对照组（44.19％ vs.19.05％,P＜0.05）;两组毒副反应发生率比较差异无统计学意义（P＞0.05）.结论 胃肠道肿瘤患者采用腹腔热灌注化疗治疗临床效果显著.
Objective To investigate clinical effect of intraperitoneal hyperthermic perfusion chemotherapy in the treatment of gastrointestinal cancer.Methods 85 cases of gastrointestinal cancer were divided into observation group （n=43） and control group （n=42） according to random number table.Control group was treated with intravenous chemotherapy treatment,observation group was treated with intraperitoneal hyperthermic perfusion on the basis of control group.Compared clinical efficacy,quality of life and toxic side effects of two groups.Results The total effective rate of observation group was significantly higher than that of control group （65.12% vs.40.48%,P〈0.05）;the improvement rate of QOL of observation group was significantly higher than that of control group （44.19% vs.19.05%,P〈0.05）;there was no statistically significant difference in the incidence of toxic side effects between two groups （P〉0.05）.Conclusion Intraperitoneal hyperthermic perfusion chemotherapy in the treatment of gastrointestinal cancer has significant clinical effect.
出处
《国际医药卫生导报》
2015年第10期1377-1379,共3页
International Medicine and Health Guidance News
关键词
胃肠道肿瘤
腹腔热灌注
化疗
Gastrointestinal cancer
Intraperitoneal hyperthermic perfusion
Chemotherapy
