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盐酸多奈哌齐治疗老年痴呆的临床探析 被引量:2

The Clinical Analysis of Donepezil Hydrochloride in the Treatment of Senile Dementia
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摘要 目的探讨盐酸多奈哌齐治疗老年痴呆的临床探析。方法选取2013年11月到2014年12月我院接诊的42例老年痴呆患者,随机分为两组,实验组22例和对照组20例,对照组给予常规治疗,实验组在对照组的基础上给予盐酸多奈哌齐,观察两组患者的治疗效果。结果实验组患者的简易智能精神状态检查量表(MMSE)评分、日常生活能力量表(ADL)评分及不良反应的发生率明显优于对照组,差异显著,有统计学意义(P<0.05)。结论盐酸多奈哌齐治疗老年痴呆的效果显著,有效改善患者的精神状态,提高患者的日常生活能力,值得临床推广。 Objective To study the clinical analysis of senile dementia on donepezil HCL treatment. Methods To divide the 42 cases patients into control group (22 cases)and experimental group(20 cases). The patients’cases were chosen from November 2013 to December 2014,the control group adopted conventional treatment,the experimental group adopted the basis of the control group combine with donepezil HCL,to observe the two groups’ therapeutic effect. Results The date of experimental group patients from simple intel igence scale for mental state examination score(MMSE),daily life ability scale score(ADL)and the incidence of adverse reaction was better than control group,it was in a high treatment efficiency and obvious difference and the statistical y significant(P〈 0.05). Conclusion Donepezil HCL treatment has significantly effectively on the patients&#39; mental state and the ability of the patients&#39; daily life. It is widely used in clinical promotion.
作者 祝鸿雁
机构地区 黑龙江省医院
出处 《中国卫生标准管理》 2015年第9期199-200,共2页 China Health Standard Management
关键词 盐酸多奈哌齐 老年痴呆 常规治疗 Donepezil HCL Senile dementia Conventional treatment
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  • 1李晶,孙蓉,马涤辉,张昱.盐酸多奈哌齐治疗轻中度老年痴呆的临床研究[J].中国老年保健医学,2006,4(2):21-22. 被引量:8
  • 2杨红,朱德生.盐酸多奈哌齐治疗老年痴呆的疗效研究[J].中国全科医学,2013,16(8):853-856. 被引量:112
  • 3中华全国中医学会.老年呆病的诊断辨证分型及疗效评定标准[J].中医杂志,2009;32(2):561-562.
  • 4Lane RM,Potkin SG,Enz A. Targeting acetylcholinesterase and butyrylcholinesterase in dementia[J].International Journal of Neuropsychopharmacology,2006,(01):101-124.
  • 5Ferri CP,Prince M,Brayne C. Global prevalence of dementia:a Delphiconsensus study[J].The Lancet,2005,(9503):2112-2117.
  • 6McKay J,Mensah GA,Greenlund K. The Atlas of Heart Disease and Stroke[M].Geneva:World Health Organization,2004.
  • 7Prince M,Ferri CP,Acosta D. The protocols for the 10/66 dementia research group population-based research programme[J].BMC Public Health,2007.165.
  • 8Prince M,Acosta D,Ferri CP. Dementia incidence and mortality in middle-income countries,and associations with indicators of cognitive reserve:a 10/66 Dementia Research Group population-based cohort study[J].The Lancet,2012,(9836):50-58.
  • 9Peltz CB,Corrada MM,Berlau DJ. Incidence of dementia in oldest-old with amnestic MCI and other cognitive impairments[J].Neurology,2011,(21):1906-1912.
  • 10Jorm AF,Jolley D. The incidence of dementia:a meta-analysis[J].Neurology,1998,(03):728-733.

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  • 1于欣,王华丽,李淑然,陈玉芳,李海东,贺军.ADAS-Cog中文版区分轻、中度阿尔茨海默病的能力[J].中国心理卫生杂志,2005,19(1):31-33. 被引量:24
  • 2曹鉴萍,张志耘.川芎嗪影响脑血管疾病的作用机制及研究进展[J].辽宁中医学院学报,2006,8(2):123-125. 被引量:10
  • 3丁玉琴,徐持华.女贞子对D-半乳糖致衰老小鼠学习和记忆的影响[J].解放军预防医学杂志,2006,24(4):247-249. 被引量:16
  • 4彭静山,点校.华佗神医秘传[M].沈阳:辽宁科学技术出版社,1982:76.
  • 5Matthews HP,Korbey J,Wilkinson DG,et al.Donepezil in Alzheimer's disease:eighteen month results from Southampton Memory Clinic.[J].Int J Geriatr Psychiatry,2000,15(8):713-720.
  • 6Rosen WG,Mohs RC,Davis KL.A new rating scale for Alzheimer's disease[J].Am J Psychiatry,1984,141(11):1356-1364.
  • 7Doody RS,Stevens JC,Beck C,et al.Practice parameter:management of dementia(an evidence-based review).Report of the Quality Standards Subcommittee of the American Academy of Neurology[J].Neurology,2001,56(9):1154-1166.
  • 8Rsler M,Anand R,Cicin-Sain A,et al.Efficacy and safety of rivastigmine in patients with Alzheimer's disease:international randomised controlled trial[J].BMJ,1999,318(7184):633-638.
  • 9Courtney C,Farrell D,Gray R,et al.Long-term donepezil treatment in 565 patients with Alzheimer'disease(AD2000):randomised double-blind trial[J].Lancet,2004,363(9427):2105-2115.
  • 10Lanctt KL,Herrmann N,Yau KK,et al.Efficacy and safety of cholinesterase inhibitors in Alzheimer's disease:a meta-analysis[J].CMAJ,2003,169:557-564.

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