期刊文献+

纤支镜下大剂量沐舒坦灌洗治疗高血压重度脑出血后肺部感染 被引量:7

Treatment of Larger Dose of Ambroxol Combined with Bronchoalveolar Lavage on Pulmonary Infection after Severe Cerebral Hemorrhage
暂未订购
导出
摘要 目的:观察纤维支气管镜联合大剂量沐舒坦肺灌洗对重度脑出血合并肺部感染的疗效。方法:2012年8月至2013年6月,应用纤维支气管镜下灌洗治疗重度脑出血合并肺部感染患者56例。按随机数字表法将其随机分为两组:实验组28例,沐舒坦90mg加生理盐水100ml,支气管肺泡灌洗。对照组28例,生理盐水100ml灌洗。气管切开术后第1、3、5、7天评估患者肺部感染评分。结果:气管切开术后第5、7天联合治疗组评分较对照组明显下降,差异均有统计学意义(P<0.05)。结论:大剂量沐舒坦支气管肺灌洗较单纯生理盐水灌洗治疗重度高血压脑出血合并肺部感染有较好的临床疗效。 Objective: To investigate the Effect of larger dose of ambroxol combined with bronchoalveolar lavage on pulmonary infection of tracheostomy patients after Severe cerebral hemorrhage. Methods: From August 2012 to June 2013, Fifty-six patients were chosen in our study and divided randomly into combination therapy group(larger dose of ambroxol combined with bronchoalveolar lavage,n=28) and control group(bronchoalveolar lavage alone,n=28). the pulmonary infect were described by Clinical Pulmonary Infection Score. Results: Clinical Pulmonary Infection Score in the combination therapy group was significantly reduced since the 5th and 7th d(P0.05). Conclusion: Larger dose of ambroxol combined with bronchoalveolar lavage has more obvious therapeutic effect on pulmonary infection than bronchoalveolar lavage alone.
出处 《中国医药导刊》 2014年第11期1369-1370,共2页 Chinese Journal of Medicinal Guide
关键词 大剂量沐舒坦 肺灌洗 高血压脑出血 肺部感染评分 肺部感染 The large dose ambroxol Lung lavage Hypertensive cerebral hemorrhage Pulmonary infection score Pulmonary infection
  • 相关文献

参考文献9

二级参考文献34

  • 1王薇,张茁.脑血管病再发相关危险因素[J].中华老年心脑血管病杂志,2005,7(5):327-328. 被引量:7
  • 2各类脑血管疾病诊断要点[J].中华神经科杂志,1996,29(6):379-380. 被引量:33093
  • 3费舟,章翔.二次脑损伤[J].中华神经外科疾病研究杂志,2006,5(5):471-473. 被引量:42
  • 4社区获得性肺炎诊断和治疗指南[J].中华结核和呼吸杂志,2006,29(10):651-655. 被引量:3113
  • 5刘学东,吕亚丽,王波,徐德忠.老年缺血性脑卒中患者预后及其影响因素的研究[J].中华老年心脑血管病杂志,2007,9(4):240-243. 被引量:19
  • 6Pugin J,Auckenthaler R,Mili N,et al.Diagnosis of ventilator a88ociated pneumonia by bacteriologicanalysis of bronchoscopic an dnonbronchoscopic blind bronchoalveolar lavage fluid.Am Rev RespirDis,1991;143:1121-1129.
  • 7O'shaughnessy ct,Lythgoe DJ,Butcher,et al.Efforts of hypoxia on getal brain metsbolism studies in utero by p-NMR epectroscopy.Brain,1991;551 (1,2):334.
  • 8Teramoto S,SuzukiM,Ohga E,et al.Effects of ambroxol on spontane-ous or stimulated generation ofreactive oxygen speciesby bronchoalveo-lar lavage cells harvested from patientswith orwithout chronic obstruc-tive pulmonary diseases.Pharmacology,1999;59(3):135-141.
  • 9Pugin J, Auckenthaler R, Mili N, et al. Diagnosis of ventilator-associ- ated pneumonia by bacteriologic analysis of bronchos copic and non- bronchoscopic "blind" bronchoalveolar lavage fluid [ J ]. Am Rev Respir Dis,i991,143(5Ptl ) :1121-1129.
  • 10Teramoto S, SuzukiM, Ohga E, et al. Effects of ambroxol on sponta- neous or stimulated generation of reactive oxygen species by bron- choalveolar lavage ceils harvested from patients with or without chro- nic obstructive pulmonary diseases [ J ]. Pharmacology, 1999,59 ( 3 ) : 135-141.

共引文献139

同被引文献57

引证文献7

二级引证文献46

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部