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保留肾单位手术和肾癌根治手术治疗局限性肾癌的临床疗效 被引量:13

Clinical Comparison of Nephron Sparing Surgery and Radical Nephrectomy in the Treatment for Patients with Focal Renal Carcinoma
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摘要 目的比较保留肾单位手术(NSS)和肾癌根治手术(RN)对局限性肾癌的临床应用可行性及疗效。方法回顾性分析2010年1月至2014年1月济南军区总医院收治的124例局限性肾癌患者的病例资料,根据术式分为保留肾单位手术61例(NSS组)和肾癌根治手术63例(RN组),比较两组患者手术时间、术中出血量、住院时间、术后引流管放置时间以及远期预后效果。结果 RN组手术时间、术中出血量、住院时间均高于NSS组[(142±32)min比(104±22)min,(302±128)m L比(165±87)m L,(14±4)d比(9±4)d,P<0.05或P<0.01],两组术后引流管放置时间比较差异无统计学意义(P>0.05);两组患者远期并发症发生率、肿瘤复发率、患者病死率比较,差异均无统计学意义(均P>0.05)。结论两种术式治疗局限性肾衰竭的临床效果肯定,保留肾单位手术较肾癌根治手术具有微创、恢复快、住院短、复发少等优势。 Objective To evaluate the clinical application feasibility and efficacy of the retention nephron sparing surgery(NSS) and radical surgery(RN) for limited focal renal cell carcinoma.Methods A total of 124 patients with focal renal carcinoma in Jinan Military General Hospital from Jan.2010 to Jan.2014 were selected and given a retrospective analysis,which according to the procedure were divided into a group with 61 cases receiving nephron sparing surgery(NSS group) and a group with 63 cases receiving radical surgery(RN group).The operation time,intraoperative bleeding amount,hospitalization days,and the postoperative remaining period of drainage tube were compared between the two groups.Results The NSS group' s operation time,intraoperative blood loss,and hospital stay were all higher than the RN group[(142 ± 32)min vs(104 ± 22) min,(302 ± 128) m L vs(165 ± 87) m L,(14 ± 4) d vs(9 ± 4) d,P〈0.05 or P〈0.01],and postoperative drainage tube remaining time was not statistically significantly different between the two groups(P〈0.05); the long-term complications,recurrence of tumor,mortality rate of the two groups were not statistically significantly different(P〉0.05).Conclusion The two kinds of operative methods for treatment of focal renal carcinoma have affirmative effect,and the NSS is featured with the advantages of minimally invasive,quick recovery,shorter hospitalization and less recurrence.
作者 沈弋桢
出处 《医学综述》 2015年第7期1292-1293,共2页 Medical Recapitulate
关键词 局限性肾癌 保留肾单位手术 肾癌根治手术 Focal renal carcinoma Nephron sparing surgery Radical nephrectomy
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