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正交t值法在中药方剂961的主药分析中的应用 被引量:15

Application of orthogonal t value method in analyzing the primary drugs in compound 961, a traditional Chinese medicine
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摘要 目的分析由10味中药组成的方剂961的主药。方法采用孙卫民和孙瑞元提出的正交t值法。结果和结果精简了处方 ,组成含6味中药的新复方962 ,并且验证了962的药效。我们认为正交t值法在中药较大方剂的研究中值得推广 ;同时还应考虑疾病的特点和中药的功效 。 Aim To analyze the primary drugs of compound 961, which is composed of 10 traditional Chinese drugs. Methods The experimental design was made by the orthogonal t value method put forward by Sun WM and Sun RY. Results and Conclusion A simplified and more effective recipe compound 962, consisting of 6 drugs was formulated and preparedand its pharmacological efficacy was verfied.The use of orthogonal t value method merits wider application in studying multiingredient recipes of traditional Chinese medicine. The characteristics of the disease, the pharmacological effects of the traditional Chinese drugs, the use of multiple animal models and mutiple parameters are factors that require consideration in research.
出处 《中国临床药理学与治疗学杂志》 CSCD 1998年第2期89-93,共5页
基金 北京市科委资助项目 北京市中医药管理局资助项目
关键词 正交T值法 中药方剂 主药分析 应用 老年期痴呆 orthogonal t value method animal model
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