摘要
背景:临床中实施常规的椎间融合器椎间融合技术可以减轻腰椎管狭窄患者的腰椎疼痛,缓解神经压迫,增强脊柱稳定性,但远期疗效有限且治疗费用较高。目的:探讨颗粒骨打压植骨在腰椎管狭窄症腰椎后路融合修复中应用的效果。方法:选择L3-S1腰椎管狭窄症患者57例,随机分两组治疗,观察组(n=27)采用自体颗粒骨打压植骨联合椎弓根钉进行椎间融合,对照组(n=30)采用椎间融合器进行椎间融合。对比两组患者治疗前、治疗后1个月及末次随访目测类比评分、ODI评分,以及住院费用和下床活动时间等指标。结果与结论:两组治疗前目测类比评分、ODI评分比较差异无显著性意义,观察组治疗后1个月、末次随访目测类比评分与ODI评分均明显低于对照组(P<0.05)。观察组住院费用明显低于对照组(P<0.05),两组治疗后下床活动时间与末次随访临床疗效优良率比较差异无显著性意义。结果表明颗粒骨打压植骨联合椎弓根钉治疗腰椎管狭窄症具有显著的临床疗效,可以有效减轻患者机体疼痛,促进腰椎功能恢复且费用低。
BACKGROUND：Clinical usage of fusion cage for interbody fusion can reduce lumbar pain of patients with lumbar spinal stenosis, relieve nerve compression, and enhance the stability of the spine, but the limited long-term efficacy and high cost of treatment are two problems to be solved. OBJECTIVE：To investigate the therapeutic effect of the granular bone grafting in the posterior lumbar fusion operation. METHODS：Fifty-seven patients with L3-S1 lumbar spinal stenosis were randomly assigned into two groups： pedicle screw＋granular bone to suppress interbody fusion in 27 patients （observation group） and interbody fusion cage for interbody fusion in 30 patients （control group）. Visual analog scale score, Oswestry disability index, hospitalization expenses and the bed activity time were compared between the two groups before treatment, 1 month after treatment and at the last folow-up. RESULTS AND CONCLUSION：There were no differences in the visual analog scale score and Oswestry disability index between the two groups before treatment, but at 1 month after treatment and at the last folow-up, these two scores were significantly lower in the observation group than the control group （P and promoting the functional recovery of the lumbar vertebra with low cost.
出处
《中国组织工程研究》
CAS
北大核心
2015年第8期1211-1215,共5页
Chinese Journal of Tissue Engineering Research
