摘要
目的：调查某中医院ICU抗菌药物的应用及细菌学情况，分析细菌耐药性，对抗菌药物使用情况进行评价。方法：利用Excel对ICU病房2003年1～12月抗菌药物的使用情况、细菌检查结果及其耐药性进行回顾性分析。结果：各类抗菌药物使用按DDDs排序，前三位分别为头孢菌素类（793.3）、碳青霉烯类（687.8）、四环素类（251.0）；按使用总量排序，前三位分别为美罗培南（1353.0g）、头孢哌酮舒巴坦（883.0g）、哌拉西林他唑巴坦（877.5g）。2013年ICU送检标本检出的146株细菌中，G-菌占82.2%，共120株，其中鲍曼不动杆菌64株；真菌占11.6%，共17株，其中白假丝酵母菌11株；G＋菌占6.2%，共9株。结论：ICU抗菌药物使用特点符合检出细菌分布情况，细菌耐药性与抗菌药物的DDDs呈正相关性。
Objective：Investigate applications of antimicrobial agents and bacteriological conditions in ICU of Hospital of TCM,analyze bacterial resistance and evaluate the reasonableness of the use of antimicrobial drugs. Method： Retrospective analyze the use of antimicrobial drugs, the results of bacteria test and its resistance in 2013 by Excel. Results： Sort by DDDs, the top three were cephalosporins（793.3）, carbapenems（687.8）, tetracyclines（251.0）;Sorted by the total amount of use, the top three were meropenem （1353.0g）, cefoperazone sulbactam （883.0g）, piperacillin tazobactam （877.5g）. In 146 cases of detected bacteria, G-accounted for 82.2%, a total of 120, including Acinetobacter baumannii 64; Fungi accounted for 11.6%, a total of 17, including Acinetobacter baumannii 11;G＋accounted for 6.2%, a total of 9.Conclusion： Antimicrobial drug use characteristics consistent with the distribution of the detection of bacteria in ICU, bacterial resistance and antimicrobial drugs DDDs were positively correlated.
出处
《北方药学》
2015年第4期112-114,共3页
Journal of North Pharmacy
关键词
抗菌药物
细菌耐药性
用药频度
合理用药
Antibacterial drugs
Bacterial resistance
DDDs
Rational use of antibiotic
