摘要
目的慢性疼痛合并抑郁、焦虑障碍住院患者予抗抑郁抗焦虑药物治疗后,观察其治疗效果。方法将56例患者分为两组,分别服用文拉法辛和帕罗西汀治疗。患者治疗前后采用Zung氏抑郁自评量表(SDS)、焦虑自评量表(SAS)进行评定。结果连续治疗3周后,两组SAS、SDS评分均下降,但文拉法辛组与帕罗西汀组相比下降程度更为显著(P<0.01);且文拉法辛治疗组的临床治疗效果总体评价优于帕罗西汀组(χ2=8.64,P<0.05)。结论文拉法辛治疗慢性疼痛伴抑郁、焦虑效果优于帕罗西汀,故可在临床上将文拉法辛进一步推广使用。
Objective After chronic pain inpatients with depression and anxiety disorder were treated with antidepressant and anxiolytic drug, then observed its curative effect. Methods 56 patients were divided into two groups, respectively taking Venlafaxine and Paroxetine therapy. Patients were evaluated by ZUNG＇s self rating Depression Scale （SDS） and self ratiug Anxiety Scale （SAS） assessment heforo and after therapy. Results After 3 weeks of continuous treatment, two groups of SAS, SDS scores decreased, but Venlafaxine group decreased more significantly than Paroxetine group （P 〈 0. 01 ） ; and Venlafaxine group on overall evaluation of clinical treatment effect was better than that of Paroxetine group （ X2 = 8.64, P 〈 0. 05 ）. Conclusions Venlafaxine in the treatment of chronic pain accompanied by depression and anxiety effect is better than that of Paroxetine, so Venlafaxine should be further promoting used in clinic.
出处
《齐齐哈尔医学院学报》
2015年第6期847-849,共3页
Journal of Qiqihar Medical University
关键词
慢性疼痛
伴抑郁焦虑
疗效比较
Chronic pain
Accompanied by depression and anxiety
Comparison of curative effect
