摘要
目的:对比奥美拉唑与法莫替丁治疗高能量多发骨折伴应激性消化系出血的临床效果.方法:选取2012-01/2013-12西宁市第二人民医院90例高能量多发骨折伴应激性消化系出血患者为研究对象,将其按照随机数字表法分为A组与B组,均45例.A组给予奥美拉唑治疗,B组给予法莫替丁治疗,观察两组的临床治疗效果.结果:A组临床治疗有效率高于B组(91.1%vs71.1%),差异无统计学意义(P<0.05);A组止血时间为低于B组(8.2 h±2.4 h vs 14.5 h±3.4 h),差异有统计学意义(P<0.05);A组不良反应发生率低于B组(11.1%vs 26.7%),差异有统计学意义(P<0.05).结论:临床中对于高能量多发骨折伴应激性消化系出血患者应用奥美拉唑的临床效果明显的优于法莫替丁,且不良反应少,值得临床中应用与推广.
AIM： To compare the clinical effects of famotidine and omeprazole in the treatment of stress-induced gastrointestinal bleeding in patients with high energy multiple fractures. METHODS： Ninety patients with high energy multiple fractures who had stress-induced gastrointestinal bleeding and were treated at the Second People＇s Hospital of Xining City from January 2012 to December 2013 were randomly and equally divided into two groups： A and B. Group A was given omeprazole, and group B received famotidine. Clinical effects were compared for the two groups.RESULTS： The effective rate was significantly higher in group A than in group B（ 91.1 % v s 71.1%, P〈0.05）. The bleeding time was significantly shorter in group A than in group B（8.2 h ± 2.4 h vs 14.5 h ± 3.4 h, P〈0.05）. The incidence of adverse reactions was significantly lower in group A than in group B（11.1% vs 26.7%, P〈0.05）. CONCLUSION： Omeprazole is superior to famotidine in the treatment of stress-induced gastrointestinal bleeding in patients with high energy multiple fractures in terms of better clinical efficacy and fewer adverse reactions.
出处
《世界华人消化杂志》
CAS
2015年第3期479-482,共4页
World Chinese Journal of Digestology
关键词
高能量
多发骨折
应激性
消化系出血
奥美拉唑
法莫替丁
High energy
Multiple fractures
Stress
Gastrointestinal bleeding
Omeprazole
Famotidine
