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电磁导航支气管镜在肺外周结节诊断中的应用 被引量:14

Electromagnetic navigation bronchoscopy in the diagnosis of peripheral lung nodules: the first study
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摘要 目的 通过临床应用,对电磁导航支气管镜技术的原理、操作过程、注意事项及应用前景进行初步探索.方法 2014年6月至7月于上海市肺科医院住院,且胸部CT发现外周结节的患者进行电磁导航支气管镜检查,术中导航成功后通过外周超声确认位置,并在X线透视下进行标本获取,送病理学检测.根据检查结果来确定电磁导航支气管镜对肺外周结节的诊断价值.结果 确诊肺癌8例,其中腺癌7例,腺、小细胞混合癌1例;1例病理阴性,抗炎治疗后病灶吸收;最初2例患者病理阴性,手术确诊为肺癌.诊断率为81.82%.导航平均(23.03±16.78) min,病灶直径(25.27±6.63)mm.无并发症发生.结论 电磁导航支气管镜是一项诊断肺外周结节的安全、有效、微创的新兴技术. Objective Electromagnetic navigation bronchoscopy(ENB) has been developed as a novel ancillary tool for the bronchoscopic diagnosis of pulmonary nodules.This study was conducted to explore its operation philosophy and application notes and foreground through clinical case analysis.Methods During the study enrollment period(June,2014 through July,2014),the ENB was performed on those patients who was detected peripheral lung nodules by chest CT.After being successfully navigated,the lesion location was confirmed by peripheral ultrasound and specimen was sampled under X-ray assistant.The specimen was finally sent to determine the pathologic classification.The diagnostic value of ENB to peripheral nodules was evaluated by the final pathologic results.Results A total of 11 patients were enrolled in this study.Among those patients,8 cases were diagnosed with lung cancer (72.7%),including 7 adenocarcinoma (63.6%) and 1 adenocarcinoma mixed with small cell carcinoma(9.1%) ; 1 case was diagnosed nagetive by pathological analysis,and lesion was absorbed after anti-inflammatory treatment ; another 2 cases was also negative by pathological analysis,but was made a definite lung cancer diagonosis after operation.In this study,overall diagonostic yield was 81.82%,the mean navigation time was(23.03 ± 16.78) min,and the mean lesion size was (25.27 ± 6.63) mm.No procedure-related complications were observed.Conclusion ENB is a new emerging technology which is safe,effective and minimally invasive in diagnosing peripheral lung nodules.
出处 《中华胸心血管外科杂志》 CSCD 2015年第2期84-87,共4页 Chinese Journal of Thoracic and Cardiovascular Surgery
基金 上海市市级医院新兴前沿技术联合攻关项目(SHDC12012111)
关键词 电磁导航 支气管镜检查 超声 介入 肺周围性病变 组织活检 Electromagnetic navigation Bronchoscopy Ultrasonography interventional Peripheral pulmonary lesion Biopsy
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