摘要
目的探讨使用洗必泰漱口液漱口对全麻患者呼吸道感染的影响。方法选取2012年1月—2013年6月某院脊柱外科行腰椎间盘摘除全麻手术患者94例,随机分为两组,各47例,对照组给予生理盐水漱口,观察组给予2%洗必泰漱口液漱口,比较两组患者呼吸道感染及咽部病原菌检出情况。结果观察组呼吸道感染发生率为8.51%(4例),对照组呼吸道感染发生率为23.40%(11例),两组呼吸道感染率比较差异有统计学意义(χ2=12.95,P<0.05)。观察组4例患者检出4株病原菌,对照组11例患者检出病原菌26株,观察组病原菌检出率低于对照组,两组比较差异有统计学意义(χ2=3.89,P<0.05)。检出病原菌以铜绿假单胞菌、金黄色葡萄球菌、肺炎克雷伯菌和大肠埃希菌为主。结论使用洗必泰漱口能有效减少全麻导致的呼吸道感染,值得临床推广应用。
Objective To evaluate the effect of chlorhexidine gargle on respiratory tract infection （RTI）in patients following general anesthesia.Methods From January 2012 to June 2013,94 patients who received general anesthe-sia for removal of vertebral disc were randomly divided into two groups,with 47 cases in each group,control group gargled with normal saline,observation group accepted 2% chlorhexidine gargle.The occurrence of RTI and detec-tion of pharynx pathogens of two groups were compared.Results The incidence of RTI in observation group and control group was 8.51%（n=4）and 23.40%（n=11）respectively（χ2 = 12.95,P 〈0.05）.4 patients in observation group were detected 4 isolates of pathogens,11 patients in control group were detected 26 isolates of pathogens,the detection rate of pharynx pathogens of observation group was lower than control group （χ2 =3.89,P 〈0.05）.The main isolated pathogens were Pseudomonas aeruginosa ,Staphylococcus aureus ,Klebsiella pneumoniae and Esche-richia coli .Conclusion Chlorhexidine gargling can effectively reduce RTI following general anesthesia,it is worthy of clinical application.
出处
《中国感染控制杂志》
CAS
北大核心
2015年第2期105-107,共3页
Chinese Journal of Infection Control
基金
攀枝花市科技基金资助项目(2014TX-10-5)
关键词
洗必泰
漱口液
侵入性麻醉
呼吸道感染
干预研究
chlorhexidine gargle
invasive anesthesia
respiratory tract infection
intervention study
