期刊文献+

缬沙坦联合培哚普利治疗糖尿病肾病的临床效果分析

Analysis of Clinical Effect of Valsartan Combined with Perindopril in Treatment of Diabetic Nephropathy
暂未订购
导出
摘要 目的:探讨缬沙坦联合培哚普利治疗糖尿病肾病的临床疗效。方法选取我院2013年3月~2014年5月收治的96例糖尿病肾病患者,将其随机分为实验组和对照组,对照组患者采用单独使用缬沙坦方法进行治疗,实验组患者在对照组方法的基础上加入培哚普利进行治疗。结果实验组采用缬沙坦和培哚普利联合治疗,实验组患者的总有效率为93.7%,明显优于对照组患者的总有效率68.9%,差异显著(P<0.05);同时两组UAER、Scr对比有显著差异,P<0.05。BUN、SBP、DBP、FBG、血钾对比无显著差异,P>0.05。结论采用缬沙坦联合培哚普利治疗糖尿病肾病效果显著,对肾组织无毒害作用,值得推广。 Objective To investigate the joint without perindopril valsartan split clinical curative effect for the treatment of diabetic nephropathy.Methods Our hospital in March 2013 ~May 2014 were treated 96 cases of diabetic nephropathy were randomly divided into experimental and control groups, the control group were treated with the use of valsartan alone method for treatment,patients in the experimental group Valerian sand Tan and perindopril treatment.Results The experimental group of valsartan and perindopril combination therapy, with a total effective rate of the experimental group were 93.7%, significantly better than the control group of patients with total efficiency of 68.9%, the difference was significant (P〈0.05); while two UAER there are significant differences, Scr contrast,P〈0.05. BUN, SBP, DBP, FBG, potassium contrast no significant difference,P〉0.05.Conclusion Valsartan combined without perindopril captopril treatment of diabetic nephropathy effect is remarkable, for renal tissue took place, worthy of promotion.
作者 王艳华
出处 《中国卫生标准管理》 2015年第6期249-250,共2页 China Health Standard Management
关键词 缬沙坦 培哚普利 糖尿病肾病 Valsartan Without perindopril split Diabetic nephropathy
  • 相关文献

参考文献3

二级参考文献48

  • 1王成,娄探奇,唐骅,彭晖,刘迅,游宇平,陈珠江,余学清.双重阻断肾素-血管紧张素系统对慢性肾脏疾病血压、蛋白尿和肾功能的影响[J].中华肾脏病杂志,2006,22(7):398-401. 被引量:35
  • 2江蓓,李宪花,杨向东,宋剑,郭玲,胡昭.贝那普利与缬沙坦联合治疗早期糖尿病肾病临床疗效观察[J].山东大学学报(医学版),2006,44(9):896-899. 被引量:12
  • 3王海燕.肾脏病学.第3版.北京:人民卫生出版社,2009.1929-1931.
  • 4Chen S,Evans T, Deng D,et al.Hyperh exosemia induced functional and structuralchanges in the kidneys:role of endothelins[J].Nephron,2002,90 (1):86-94.
  • 5Krolewski AS, Warram JH, Christlieb AR, et al. The changing natural history of nephropathy in type I diabetes. Am J Med, 1985, 78: 785-794.
  • 6Matsushima M, Tajima N, LaPorte RE, et al. Markedly increased renal disease mortality and incidence of renal replacement therapy among IDDM patients in Japan in contrast to Allegheny County, Pennsylvania, USA. Diabetes Epidemiology Research International (DERI) U S Japan Mortality Study Grouo. Diabetolozia. 1995. 38: 236.
  • 7Fioretto P, Caramori ML, Mauer M. The kidney in diabetes: dynamic pathways of injury and repair. The Camillo Golgi Lecture 2007. Diabetologia, 2008, 51 : 1347-1355.
  • 8Forsblom CM, Groop PH, Ekstrand A, et al. Predictive value of microalbuminuria in patients with insulin dependent diabetes of long duration. BMJ, 1992, 305: 1051-1053.
  • 9Caramori ML, Fioretto P, Mauer M. The need for early predictors of diabetic nephropathy risk: is albumin excretion rate sufficient? Diabetes, 2000, 49: 1399-1408.
  • 10Caramofi ML, Fioretto P, Mauer M. Enhancing the predictive value of urinary albumin for diabetic nephropathy. J Am Soe Nephrol, 2006, 17: 339-352.

共引文献97

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部