摘要
目的：探讨替硝唑在治疗加重型口腔感染时的作用。方法：随机选择2013年6月~2014年6月我院口腔科接受治疗的140例口腔感染患者作为研究对象,将患者分为研究组和参照组,研究组患者以替硝唑治疗,参照组患者以甲硝唑治疗,对比两组的近期临床效果。结果：研究组近期治疗总有效率是97.14%,高于参照组的84.28%;研究组伤口愈合的时间以及症状消失的时间,明显比参照组所用的时间短;研究组患者出现不良反应的发生率为17.14%,显著低于参照组的32.83%;差异均具有统计学意义（P〈0.05）。结论：替硝唑具有发挥药效快、不良反应少、安全系数高等优点,更适用于加重型口腔感染的治疗,有利于患者更好、更快、更安全地恢复健康。
Objective：To explore the effect of tinidazole in treatment with severe oral infection and safety. Method：randomly selected in2013 June to 2014 June in our hospital treated 140 cases of oral infection in Department of Stomatology patients as the research object,the patients were divided into the study group and the reference group, to study group patients with tinidazole treatment with metronidazole,to refer to the patients in the treatment group,compared two groups of the short-term clinical effect. Results：the study group therapeutic effect of total efficiency is 97.14%,higher than the efficiency of total 84.28% reference group;wound healing time and the study group the symptoms disappear time,significantly more than the reference group for a short time;probability of groups of patients with adverse reactions was 17.14%,significantly lower than the reference group of 32.83%. The difference was statistically significant（P〈0.05）. Conclusion：tinidazole has fast effect,less adverse reaction,the advantages of higher safety coefficient,more suitable for patients with treatment of severe oral infection,can help patients better,faster,more secure recovery.
出处
《北方药学》
2015年第3期39-40,共2页
Journal of North Pharmacy
关键词
替硝唑
口腔感染
临床疗效
安全性
Tinidazole
Oral infection
Clinical efficacy
Safety
