摘要
目的:观察砂附汤治疗慢性萎缩性胃炎的临床疗效和安全性。方法:将108例慢性萎缩性胃炎患者,按随机数字表法分为治疗组和对照组,其中治疗组患者58例,给予中药汤剂砂附汤治疗,每日1副;对照组患者50例,给予多潘立酮治疗,1次10 mg,1日3次,餐前服用。2组患者均服药2个月,观察治疗前后2组患者的临床症状、胃泌素等指标的变化情况。结果:治疗组患者的临床症状、胃泌素均有明显改善,均优于对照组,2组差异有统计学意义(P<0.05);2组患者均未出现不良反应。结论:砂附汤治疗慢性萎缩性胃炎有良好疗效,且安全性好。
OBJECTIVE:To evaluate the clinical efficacy and safety of Shafu soup for atrophic gastritis. METHODS:A total of 108 patients with atrophic gastritis were randomized to either treatment group ( 50 cases ) or control group(58 cases) .The treatment group received Shafu soup and the control group received Domperidone tablets (10 mg each time preprandial t.i.d) for two months.The changes in clinical symptoms and gastrin level of the two groups were followed.RESULTS:The improvement in clinical symptoms and gastrin level in the patients treated with Shafu soup were significantly better than in the control group ( P〈0.05 ) , and two group of patients without adverse reactions.CONCLUSIONS:Shafu soup is safe and effective for atrophic gastritis.
出处
《中国医院用药评价与分析》
2014年第11期993-995,共3页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
砂附汤
慢性萎缩性胃炎
多潘立酮
Shafu soup
Atrophic gastritis
Domperidone tablets