摘要
目的:研究保妇康栓治疗宫颈人乳头瘤病毒(HPV)感染的临床疗效。方法:采用多中心随机对照研究,选择6家医院的宫颈HPV感染者共243例,随机分为保妇康栓组161例,空白对照组82例,分析比较两组疗效;选择感染不同HPV亚型的患者,分为保妇康栓组和空白对照组,比较两组的疗效。结果:治疗HPV感染4个月、8个月后,保妇康栓组的总有效率优于空白对照组,两组总有效率比较差异有统计学意义(P<0.01);保妇康栓治疗高危型HPV68、52、53、16、18的转阴率分别为91.67%、84.85%、83.33%、70.73%、70.00%,高于空白对照组,但差异无统计学意义(P>0.05);HPV52和HPV68感染的患者保妇康栓组治疗后转阴率(84.85%、91.67%)与空白对照组(27.27%、42.86%)比较,差异有统计学意义(P<0.05)。结论:保妇康栓能有效清除HPV病毒,使HPV感染患者转阴,值得临床推广。
Objective： To evaluate the effect of Baofukang suppository on treatment of HPV infection.M ethods： 243 cases with cervical HPV infection in 6 hospitals were enrolled in this study,who were assigned into treatment group（ Baofukang suppository,161 cases）,and control group（ 82 cases）. The effect on HPV infection was compared between two groups. Results： The total effective rate in Baofukang suppository group was higher than that in control group after 4 months and 8 months（ P〈0. 05）. The effective rate of Baofukang suppository on HPV68 /52 /53 /16 /18 was over 70%,and there was a significant difference for HPV 68 and 52 in comparison with control group（ P〈0. 05）. Conclusions： Baofukang suppository should be an effective treatment method for HPV infection.
出处
《实用妇产科杂志》
CAS
CSCD
北大核心
2015年第1期45-48,共4页
Journal of Practical Obstetrics and Gynecology
关键词
保妇康栓
人乳头瘤病毒
高危型
Baofukang suppository
Human papillomavirus
High-risk type
