摘要
目的观察针刺调理脾胃升降法对脾虚型肠易激综合征患者泄泻症状的疗效及对血清血管活性肠肽(vasoactive intestinal peptide,VIP)、5-羟色胺(5-hydroxytryptam ine,5-HT)水平的影响。方法将60例脾虚型肠易激综合征患者随机分为治疗组和对照组,每组30例。治疗组采用针刺调理脾胃升降法治疗,对照组采用口服匹维溴铵治疗。治疗4星期后观察两组治疗前后的泄泻症状评分及血清血管活性肠肽、5-HT含量的变化。结果治疗组治疗后泄泻症状评分、血清VIP及5-HT含量与对照组比较,差异均具有统计学意义(P<0.05)。两组治疗后泄泻症状评分、血清VIP及5-HT含量与同组治疗前比较,差异均具有统计学意义(P<0.05)。结论针刺调理脾胃升降法是一种治疗肠易激综合征脾虚型泄泻的有效方法,能有效调节患者血清VIP及5-HT含量。
Objective To investigate the efficacy of ascending-descending acupuncture method regulation of the spleen and stomach in treating spleen deficiency-type diarrhea in irritable bowel syndrome and its effect on serum vasoactive intestinal peptide （VIP） and 5-hydroxytryptamine （5-HT） levels. Methods Sixty irritable bowel syndrome patients with spleen deficiency-type diarrhea were randomly allocated to treatment and control groups, 30 cases each. The treatment group received ascending-descending acupuncture method regulation of the spleen and stomach and the control group, oral administration of pinaveriurn bromide. The symptom of diarrhea was scored and the vasoactive intestinal peptide and 5-hydroxytryptamine contents of serum were measured in the two groups before and after four weeks of treatment. Results There were statistically significant post-treatment differences in the diarrhea symptom score and serum vasoactive intestinal peptide and 5-hydroxytryptamine contents between the treatment and control groups （P〈0.05）. There were statistically significant pre-/post-treatment differences in the diarrhea symptom score and serum vasoactive intestinal peptide and 5-hydroxytryptamine contents in the two groups （P〈0.05）. Conclusion Ascendingdescending acupuncture method regulation of the spleen and stomach is an effective way to treat spleen deficiency-type diarrhea in irritable bowel syndrome. It can effectively regulate the vasoactive intestinal peptide and 5-hydroxytryptamine contents of serum in the patients.
出处
《上海针灸杂志》
2015年第1期25-27,共3页
Shanghai Journal of Acupuncture and Moxibustion
基金
国家中医药管理局重点学科专项科研课题(ZTLX201317)
关键词
针刺疗法
肠易激综合征
腹泻
血清血管活性肠肽
5-羟色胺
脾升胃降
Acupuncture therapy
Irritable bowel syndrome
Diarrhea
Serum vasoactive intestinal peptide
5-hydroxytryptamine
Spleen-qi ascending stomach-qi descending
