摘要
目的 :探讨纳络酮注射液在治疗急性脑卒中的剂量及方法。方法 :观察95例脑卒中 (梗死及出血 )病人 ,随机分为治疗组和对照组。在常规治疗的基础上 ,治疗组加用纳络酮每天10mg左右 (不大于12mg)记录并分析其疗效及副作用。结果 :(1)在不同剂量的治疗组与对照组相比较 ,其GCS评分均有提高 ,24小时后差异有显著性。(2)对脑梗死及脑出血并昏迷 ,治疗组均显示一定的催醒作用。(3)未见任何与本药相关的副作用。结论 :纳络酮具有良好的催醒作用 ,对急性脑卒中的治疗有效 ,10mg/日的剂量是安全而有效的 。
Objective:To study the treatment method and dosage of naloxone in the treatment of acute cerebral apoplexy.Methods:95 patients with cerebral apoplexy(infarction and hemorrhage) were divided into treatment group and control group in randomly.The routine method was adopted in the control group.In the treatment group,based on conventional treatment the naloxone was used 10mg once a day(≥12mg).The effect and side effect were recorded and analysed.Results:GCS of all the patients in the two groups was increasing after administration.compared with the control group in different dosage.there was significant difference after 24 hous between them.There were some hypnotic actions in the patients of cerebral infarction and hemorrhage with coma in the treatment group.The relation side effect of this drug was not found.Conclusion:Naloxone has a good hypnotic action and curative effect for acute cerebral apoplexy.The dosage of 10mg/day is effective and safe.It may be spread extensively in clinical practice. [
出处
《现代医药卫生》
2002年第8期651-653,共3页
Journal of Modern Medicine & Health
