摘要
目的：分析卵巢移行细胞癌的临床病理特点。方法收集2000～2013年收检的10例卵巢移行细胞癌病例，复习临床资料，并观察病理形态学特点。结果患者年龄36～61岁，中位年龄56岁。10例均行手术治疗，术后化疗采用 TP 方案或 CAP 方案。8例获得随访，2例死亡，6例存活。病理组织学检查显示移行细胞癌的特点，不伴有 Brenner 瘤结构。免疫组化表达 WT-1、CK7、P53、CA125，不表达 CK20和 UroplakinⅢ。结论卵巢移行细胞癌具有特殊的形态学和免疫组化特点，不同于 Brenner 肿瘤，支持卵巢移行细胞癌实际是高级别的浆液性癌的观点。
Objective To analyze the clinical and pathological features of ovarian transitional cell cacinomas （TCC）. Methods 10 cases of TCC were collected from 2000 to 2013. The clinical, pathological features of all were evaluated. Results The patients’ age ranged from 36 to 61 years （mean 56 years）. 10 cases underwent surgery and postoperative chemotherapy with TP or CAP program. The follow-up of 8 cases found that 2 cases died and 6 cases survived. Histopathological examination showed the features of transitional cell carcinoma without the structure of Brenner tumor （BT）. Immunohistochemically, all TCCs were positive for WT-1, CK7, P53 and CA125, while all were negative for CK20 and UroplakinⅢ. Conclusion TCC with special morphological and immunohistochemical features, is different from BT. Conclusions support the view that TCC actually is one of high-grade serous adenocarcinomas.
出处
《中华临床医师杂志（电子版）》
CAS
2015年第1期52-55,共4页
Chinese Journal of Clinicians(Electronic Edition)
关键词
卵巢肿瘤
病理学
移行细胞癌
Ovarian neoplasms
Pathology
Transitional cell carcinoma
