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炎症性肠病初次发病与季节分布相关性分析 被引量:4

Association between seasonal variation and first attack in patients with inflammatory bowel disease
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摘要 炎症性肠病(inflammatory bowel disease,IBD)是一种慢性非特异性肠道炎性疾病,包括溃疡性结肠炎(ulcerative colitis,UC)和克罗恩病(Crohn's disease,CD)[1]。目前认为IBD的发病主要与环境、遗传以及机体免疫因素相关[2]。近年,环境因素在IBD的发病机制中所扮演的角色受到广泛的关注[3]。
出处 《中国实用内科杂志》 CAS CSCD 北大核心 2014年第12期1206-1207,共2页 Chinese Journal of Practical Internal Medicine
基金 湖北省科技支撑计划项目(2013BCB006)
关键词 炎症性肠病 发病时间 季节 inflammatory bowel disease time of morbidity season
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  • 2[2]Fell JM,Paintin M,Arnaud-Battandier F,Beattie RM,Hollis A,Kitching P,Donnet-Hughes A,MacDonald TT,Walker-Smith JA.Mucosal healing and a fall in mucosal pro-inflammatory cytokine mRNA induced by a specific oral polymeric diet in paediatric Crohn's disease.Aliment Pharmacol Ther 2000;14:281-289
  • 3[3]Teahon K,Pearson M,Smith T,Bjarnason I.Alterations in nu tritional status and disease activity during treatment of Crohn's disease with elemental diet.Scand J Gastroenterol 1995;30:54-60
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  • 6[6]Andus T,Daig R,Vogl D,Aschenbrenner E,Lock G,Hollerbach S,Kollinger M,Scholmerich J,Gross V.Imbalance of the interleukin 1 system in colonic mucosa-association with intestinal inflammation and interleukin 1 receptor antagonist [corrected] genotype 2.Gut 1997;41:651-657
  • 7[7]Casini-Raggi V,Kam L,Chong YJ,Fiocchi C,Pizarro TT,Cominelli F.Mucosal imbalance of IL-1 and IL-1 receptor antagonist in inflammatory bowel disease.A novel mechanism of chronic intestinal inflammation.J Immunol 1995;154:2434-2440
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