摘要
目的探讨瞬时波强(WI)技术对糖调节受损患者胫前动脉的弹性变化及意义。方法根据空腹血糖值及口服葡萄糖耐量试验血糖值把研究对象分为3组:A组(血糖正常组),B组(新增空腹血糖受损组),C组(糖尿病前期组),分别测定各组下肢胫前动脉WI的以下指标:血管压力应变弹性系数(Eρ)、僵硬度(β)、增大系数(AI)、顺应性(AC)、脉搏波传导速度(PWVβ)、负向面积(NA)。结果与A组对比,C组的β、Eρ、PWVβ差异有统计学意义(P<0.05);B组的β、Eρ、AI、PWVβ、NA和C组的AI、NA有增加趋势,但差异无统计学意义(P>0.05);B、C组的AC差异无统计学意义(P>0.05)。结论糖尿病前期胫前动脉已出现弹性减低,WI技术对糖调节受损下肢动脉病变的早期预测具有重要价值。
Objective To explore the change of anterior tibial artery elasticity in patients with impaired glucose regulation by wave intensity （WI） technique.Methods A totle of sixty-nine patients were enrolled and divided into 3 groups according to their plasma glucose levels：patients were categorized as normal plasma glucose group （group A,n =25）,newly categorized impaired fasting glucose group （group B,n =22） and pre-diabetes group （group C,n =22）.WI examination of anterior tibial artery were performed in all the patients.The parameters included nagative area（NA）,stiffness parameter（β）,pressure strain elasticity modulus（Ep）,arterial compliance（AC）,augmentation index（AI） andone point pulse wave velocity（PWVβ）.Results Compared with group A,stiffness parameter （β）,pressure strain elasticity modulus （Ep） and one point pulse wave velocity （PWVβ） levels of C group were higher （P ＜ 0.05）.In group B,these indicators elevated slightly（P ＞ 0.05）.Furthermore,there was no significant difference in AC and NA between 3 groups（P ＞ 0.05）.Conclusion The elasticity of anterior tibial artery decreases in patients with impaired Pre-diabetes stage.WI technique can be used in diagnosing and preventing diseases of lower limb artery in patients with impaired glucose regulation in early stage.
出处
《医学研究杂志》
2014年第11期93-95,共3页
Journal of Medical Research
基金
郑州市科技攻关计划项目(2010SFXM175)
关键词
瞬时波强
糖调节受损
胫前动脉
动脉弹性
Wave intensity
Impaired glucose regulation
Anterior tibial artery
Elasticity of artery
