摘要
基于中药的多成分特点,借鉴化药领域的生物药剂学分类系统(biopharmaceutics classification system,BCS)理念、方法和技术,提出了中药生物药剂学分类系统(biopharmaceutics classification system of Chinese materia medica,CMMBCS)的科学框架。在学术思想阐述和理论分析的同时,构建了基于多成分层次差异比较法和中药整体CMMBCS研究法的方法流程,明确了该系统用于揭示中药多成分吸收的相互影响及相关机制的基础性作用,也为提高中药质量标准和开发中药新药提供了新的思路和方法。
Based on the characteristics of muhicomponent of traditional Chinese medicine and drawing lessons from the con- cepts, methods and techniques of biopharmaceutics classification system （BCS） in chemical field, this study comes up with the science framework of biopharmaceutics classification system of Chinese materia medica （CMMBCS）. Using the different comparison method of multicomponent level and the CMMBCS method of overall traditional Chinese medicine, the study constructs the method process while setting forth academic thoughts and analyzing theory. The basic role of this system is clear to reveal the interaction and the related absorption mechanism of multicomponent in traditional Chinese medicine. It also provides new ideas and methods for improving the quality of Chinese materia medica and the development of new drug research.
出处
《中国中药杂志》
CAS
CSCD
北大核心
2014年第23期4479-4483,共5页
China Journal of Chinese Materia Medica
基金
国家自然科学基金项目(81473362)
关键词
生物药剂学分类系统
中药生物药剂学分类系统
构建分析
biopharmaceutics classification system
biopharmaceutics classification system of Chinese materia medica
construction analysis
