期刊文献+

老年肺硬化性血管瘤的诊治分析(附86例报告) 被引量:1

暂未订购
导出
摘要 目的总结老年肺硬化性血管瘤(PSH)的临床表现、病理学特征、影像学特点及鉴别诊断。方法回顾性分析86例老年PSH患者的临床病理资料,对其临床特征、影像学检查结果和病理诊断特点等进行分析。结果老年PSH多见于女性,常无明显临床症状或表现为咳嗽、咳痰等轻微的非特异性症状。影像学上均表现为圆形或类圆形肺内孤立性结节,但均未见有新月征。病理学检查示老年PSH由圆形间质细胞和表面细胞构成,镜下可分为乳头状结构、实性结构、血管瘤样区和硬化性结构。免疫组化检查以TTF-1、EMA、AE1/3和Syn阳性表达为主。结论老年PSH临床特征不典型,易于误诊;胸部CT扫描虽有助于鉴别与诊断,但最终确诊需依靠组织病理学,当无法确诊时,首选手术探查切除且预后良好。
出处 《宁夏医学杂志》 CAS 2014年第11期1044-1046,共3页 Ningxia Medical Journal
  • 相关文献

参考文献10

  • 1Neumar J,Rosioreanu A,schuss A,et al.Radiology-pathology conferen:sclerosing hemangioma of the lung[J].Clin Imaging,2006,30(6):409.
  • 2Liebow AA,Hubbell DS.Sclerosing hemangioma histiocytoma,xanthoma of the lung[J].Cancer,1956,9(1):53-57.
  • 3Wang QB,Chen YQ,Shen JJ,et al.Sixteen cases of pulmonary sclerasing haemangioma:CT findings are not definitive for preoperative diagnosis[J].Clin Radiol,2011,66(8):708.
  • 4蔡奕欣,廖永德,付向宁,张霓.肺硬化性血管瘤45例临床分析[J].临床外科杂志,2011,19(6):405-407. 被引量:5
  • 5Lee E,Park CM,Kang KW,et al.18F-FDG PET/CT features of pulmonary sclerosing hemangioma[J].Acta Radiol,2013,54(1):24-29.
  • 6Jungraithmayr W,Eggeling S,Luduig C,et al.Sclerosing hemangioma of the lung:a benigh tumor with potential for malignancy[J].Ann Thorac Cardiovasc Surg,2006,12(5):352.
  • 7马少华,孙宇,杜长征,梁震,熊宏超,陈克能.肺硬化性血管瘤的诊治[J].中国肺癌杂志,2011,14(8):674-678. 被引量:14
  • 8Chen B,Gao J,Chen H,et al.Pulmonary sclerosing hemangioma:a unique epithelial neoplasm of the lung(report of 26 cases)[J].World J Surg 0ncol,2013,11:85.
  • 9陆沈栋,凌春华.肺硬化性血管瘤13例临床分析[J].安徽医药,2014,18(1):75-78. 被引量:4
  • 10Katakura H,Sato M,Tanaka F,et al.Pulmonary sclerosing heman-gioma with metastasis to mediastinallymph node[J].Ann Thorac Surg,2005,80(6):2351.

二级参考文献53

  • 1王妍,戴顺东,王恩华.所谓肺硬化性血管瘤组织中两种主要细胞的基因表达差异及意义[J].中国肺癌杂志,2007,10(6):466-470. 被引量:13
  • 2齐凤杰,张秀伟,张永兴,王恩华.p53蛋白表达和基因突变在所谓肺硬化性血管瘤组织中的意义[J].中国肺癌杂志,2006,9(2):147-151. 被引量:9
  • 3Liebow AA, Hubbell DS. Sclerosing hemangioma (histiocytoma, xanthoma) of the lung. Cancer, 1956, 9(1): 53-75.
  • 4World health organization. Histological typing of lung tumors 3rd edition. WHO, 1999.
  • 5Kalhor N, StaerkeI GA, Moran CA. So-called sclerosing hemangioma of lung: current concept. Ann Diagn Pathol, 2010, 14(1): 60-67.
  • 6Mori S. Sclerosing hemangioma of the lung. Dis Chest, 1968, 54(4): 381-384.
  • 7Haas JE, Yunis EJ, Totten RS. Ultrastructure of a sclerosing hemangioma of the lung. Cancer, 1972, 30(2): 512-518.
  • 8Spencer H, Nambu S. Sclerosing angioma of the lung. Histopathology, 1986, 10(5): 477-487.
  • 9Hill GS, Eggleston JC. Electron microscopic study of so-called "pulmonary sclerosing hemangioma". Report of a case suggesting epithelia/origin. Can- cer, 1972, 30(4): 1092-1106.
  • 10Devouassoux-Shisheboran M, Hayashi T, Linnoila RI, et al. A clinicopatho- logic study of 100 cases of pulmonary sclerosing hemangioma with immu- nohistochemical studies: TTF-1 is expressed in both round and surface cells, suggesting an origin from primitive respiratory epithelium. AmJ Surg Pathol, 2000, 24(7): 906-916.

共引文献18

同被引文献16

  • 1向萌,殷莲华.肥大细胞与血管新生[J].国外医学(生理病理科学与临床分册),2004,24(3):251-253. 被引量:8
  • 2史讯,张志勇,张兴伟,候君.肺硬化性血管瘤的CT表现与病理对照分析(附21例报告)[J].实用放射学杂志,2007,23(3):311-314. 被引量:65
  • 3Liebow AA,Hubbell DS. Sclerosing hemangioma(histio- cytoma,xanthoma)of the lung [J]. Cancer, 1956,9 (1) :53- 75.
  • 4Keylock JB, Galvin JR, Franks TJ. Sclerosing hemangioma of the lung [J]. Arch Pathol Lab Med,2009,133 (5) : 820-825.
  • 5Chen B,Gao J,Chen H,et al. Pulmonary sclerosing he- mangioma:a unique epithelial neoplasm of the lung(re- port of 26 cases)[J]. World J Surg Oncol,2013,11:85.
  • 6Schmidt LA, Myers JL, McHugh JB. Napsin A is differen- tially expressed in sclerosing hemangiomas of the lung [J]. Arch Pathol Lab Med,2012,136(12) : 1580-1584.
  • 7Lee HJ,Jang SJ,Chun SM,et al. Comparison of genetic and epigenetic alterations at 11 tumor suppressor loci in pulmonary sclerosing hemangioma and adenocarcinoma [J]. Exp Lung Res, 2011,37(6) : 344-353.
  • 8Galambos C, Levy H, Cannon CL, et al. Pulmonary pathology in thyroid transcription factor-1 deficiency syndrome [J].Am J Respir Crit Care Med,2010,82(4) : 549-554.
  • 9Boggaram V. Thyroid transcription factor-1 (TFF-1/ Nkx2.1/TITF1)gene regulation in the lung[J]. Clin Sci (Lond), 2009, 116( 1 ) :27-35.
  • 10Anan E, Shirai R, Hirat N, et al. Two cases, of pulmonary sclerosing hemangioma, and peripheral lung carcinoid,in which the diagnoses were difficult by intraoperative frozen section examinations[J]. Nihon Kokyuki Gakkai Zasshi, 2010,48 (3) : 253-259.

引证文献1

二级引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部