期刊文献+

血小板计数升高在小儿重症肺炎中的预测价值 被引量:3

暂未订购
导出
摘要 目的探讨血小板计数(PLT)升高在小儿重症肺炎中的预测价值。方法选择肺炎患儿100例,其中重症肺炎患儿50例,普通肺炎患儿50例;收集同期进行健康体检者50例,分为重症肺炎组、普通肺炎组、正常对照组3组,比较各组血小板计数水平是否存在差异。同时应用受试者工作特征(ROC)曲线下面积评价血小板计数升高在预测小儿重症肺炎的诊断价值。结果重症肺炎组患儿平均血小板计数为(452.2±20.71)×10^9/L,普通肺炎组为(386.1±19.98)×10^9/L,正常对照组为(191.6±6.88)×10^9/L;重症肺炎组和普通肺炎组患儿血小板计数均明显高于正常对照组(均P〈0.01),重症肺炎组患儿血小板计数明显高于普通肺炎组(P〈0.05)。曲线下面积为0.910,95%可信区间为0.814~0.968,当血小板诊断界值为438.0×10^9/L时,约登指数为0.7123,灵敏度为0.897,特异度为0.816,此时阳性预测值为0.788,阴性预测值为0.912,OR值为32.5,阳性似然比为4.87,阴性似然比为0.13。结论肺炎患儿血小板计数升高,重症肺炎患儿升高更明显,血小板计数升高可以作为重症肺炎的预测指标。
出处 《现代实用医学》 2014年第11期1341-1342,共2页 Modern Practical Medicine
  • 相关文献

参考文献11

  • 1Rudan I, Boschi-Pinto C, Biloglav Z, et al. Epidemiology and etiology of child- hood pneumonia[J]. Bulletin of the World Health Organization, 2008, 86(5): 408-416B.
  • 2胡亚美,江载芳.诸福棠实用儿科学[M].7版.北京:人民卫生出版社,2002:632-636.
  • 3宇传华,徐勇勇.ROC分析的基本原理[J]中华流行病学杂志,1998,19(2):413-415.
  • 4Vlacha V, Feketea G. Thrombocytosis in pediatric patients is associated with severe lower respiratory tract inflammation [J]. Archives of medical research, 2006, 37 (6): 755-759.
  • 5Heng JT, Tan AM. Thrombocytosis in childhood[J]. Singapore medical journal, 1998, 39(11): 485-487.
  • 6Othman N, lsaaes D, Kesson A. Mycop lasma pneumoniae infections in Austra- lian children[J]. Journal ofpaediatries and child health, 2005, 41(12): 671-676.
  • 7肖胜军.260例小儿支气管肺炎血小板参数的变化[J].血栓与止血学,2007,13(2):68-70. 被引量:15
  • 8Magret M, Lisboa T, Martin-Loeches I, et al. Bacteremia is an independent risk fac- tor for mortality in nosoeomial pneumonia: a prospective and observational multicen- ter study[J]. Crit Care, 2011, 15(1): R62.
  • 9李丰,张园海,邵兰,陈其.婴幼儿重症肺炎病情危重的预测指标[J].中国当代儿科杂志,2012,14(9):664-666. 被引量:14
  • 10杨峰,崔史杰.重症肺炎患儿血浆胰岛素水平与TNF-α含量的关系[J].河北医药,2007,29(9):935-935. 被引量:8

二级参考文献16

  • 1王今达,王宝恩.多脏器功能失常综合征(MODS)病情分期诊断及严重程度评分标准(经庐山’95全国危重病急救医学学术会讨论通过)[J].中国危重病急救医学,1995,7(6):346-347. 被引量:1431
  • 2无.儿童社区获得性肺炎管理指南(试行)(下)[J].中华儿科杂志,2007,45(3):223-230. 被引量:211
  • 3[5]ZHOU W G,Mecollum MO,LEVINE BA,et al.Role of platelet-aetivating factor in paucreatitis-associated acute lung injury in rats[J].Am J Pathol,1992,140:971-979.
  • 4孙芾 赵素荣.血小板分析4项参数的正常参考范围[J].中华医学检验杂志,1993,16(2):107-108.
  • 5胡亚美,江载芳,等,主编.诸福棠实用儿科学[M].第7版.北京:人民卫生出版社,2002.1 199.
  • 6Bone RC,Balk RA,Cerra FB,et al.Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis.Chest.1992,101:1644-1655.
  • 7Hotamisligil GS,Spieglman BM.Tumor necrosis factor alpha:a key component of the obesity diabets link.Diabetes,2004,53:1271-1278.
  • 8Stephens JM,Lee J,Pilch PF.TNF-ainduced insulin resistance in STSLI adipocytes is accompanied by a loss of insulin receptor-substar-1 and GLUT4 expression without a loss of insulin receptormediated signal transduction.J Biol Chen,2003,283:971-105.
  • 9Rudan I,Boschi-Pinto C,Biloglav Z,Mulholland K,CampbellH.Epidemiology and etiology of childhood pneumonia[J].BullWorld Health Organ,2008,86(5):408-416.
  • 10Lupisan SP,Ruutu P,Erma Abucejo-Ladesma P,Quiambao BP,Gozum L,Sombrero LT,et al.Predictors of death from severepneumonia among children 2-59 months old hospitalized in Bohol,Philippines:implications for referral criteria at a first-level healthfacility[J].Trop Med Int Health,2007,12(8):962-971.

共引文献1944

同被引文献23

引证文献3

二级引证文献64

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部