摘要
目的探讨血清游离脂肪酸水平与非酒精性脂肪肝病（NAFLD）及颈动脉内膜中层厚度（CIMT）间的关系。方法测定150例健康对照和168例NAFLD患者的血脂水平、胰岛素抵抗和CIMT厚度。分析影响NAFLD、CIMT的独立因素。结果NAFLD组患者较健康对照组空腹血糖、三酰甘油、空腹胰岛素、空腹游离脂肪酸及CIMT等指标均显著升高（P〈0．01）。结论游离脂肪酸水平是NAFLD患病的独立影响因素，NAFLD患者血清游离脂肪酸水平普遍升高，NAFLD患者血清游离脂肪酸水平升高与CIMT增加有关。
Objective To investigate the correlation of serum free fatty acids levels with non-alcoholic fatty liver disease （NAFLD） and carotid artery intima-media thickness （CIMT）. Methods The blood lipid levels, insulin resistance and CIMT thickness were measured in 150 healthy controls and 168 eases of NAFLD. The independent factors influencing NAFLD, and CIMT were analyzed. Results The levels of fasting blood glucose, triglycerides, fasting insulin, fasting free fatty acids and CIMT thickness were significantly higher in patients with NAFLD than those in healthy controls（P 〈0.01 ）. Conclusions Free fatty acid levels are independent risk factors of NAFLD. NAFLD patients have elevated levels of serum free fatty acids. In addition, elevated serum free fatty acid levels are correlated with CIMT.
出处
《中国实用医刊》
2014年第23期41-42,共2页
Chinese Journal of Practical Medicine
关键词
非酒精性脂肪肝病
游离脂肪酸水平
颈动脉内膜中层厚度
关系
Non-alcoholic fatty liver disease
Free fatty acid levels
Carotid artery intima-media thickness
Relations
