摘要
目的：分析丽水市中心医院嗜麦芽窄食单胞菌的来源、病区分布及耐药情况,为临床合理使用抗菌药提供依据。方法：收集分离自2009年1月-2012年12月的367株嗜麦芽窄食单胞菌,采用法国梅里埃Vitek2-Compact全自动细菌分析仪鉴定细菌,用K-B纸片扩散法进行药敏试验。结果：嗜麦芽窄食单胞菌主要来源于痰液标本,占86.6%,临床分布以ICU最高,占38.4%,对抗菌药米诺环素、左氧氟沙星、复方磺胺甲噁唑、头孢哌酮/舒巴坦的耐药率分别为6.6%,8.8%,10.4%和9.8%。结论：嗜麦芽窄食单胞菌主要分离自ICU、神经外科和呼吸内科的呼吸道标本中,该菌对多数抗菌药有固有耐药,但对米诺环素、左氧氟沙星、复方磺胺甲噁唑和头孢哌酮/舒巴坦的耐药率较低,临床应根据药敏结果合理选用抗菌药。
Objective： To provide basis for clinical rational use of antibacterial by studying the source, distribu tion and drugresistance of Stenotropomonas maltophilia in Lishui Central Hospital. Methods ：367 strains of S. maltophilia were collected from January 20009 to December 2012. Identified the bacteria strains with VITEK 2COMPACT instrument. And the drugresistance test adapted KB test. Results： S. maltophilia were mainly isolated from sputum sample, accounting for 86.6%. The clinical distribution of ICU was the highest in the hospital, accounted for 38.4%. The resistance rate of S. maltophilia to minocycline, levofloxacin, trimethoprimsulfamethoxazole and cefoperazone/sulbactam were 6.6%, 8.8%, 10.4% and 9.8%. Conclusion：The S. maltophilia were mainly isolated from specimen of sputum in ICU, neuro surgery department and respiratory medicine department. The organism was inherently resistant to most antibacterial agents, but less resistant to minocyeline, levofloxacin, trimethoprimsulfamethoxazole and cefoperazonesulbactam. The clinician should choose suitable antibiotics based on the results of drug sensitivity tests.
出处
《药物流行病学杂志》
CAS
2014年第11期664-666,共3页
Chinese Journal of Pharmacoepidemiology
关键词
嗜麦芽窄食单胞菌
耐药性
院内感染
抗菌药
Stenotropomonas maltophilia
Drug-resistance
Nosocomial infection
Antibiotics
