摘要
目的探讨莫沙必利联合前列地尔治疗糖尿病胃轻瘫(DGP)的疗效。方法选取该院2009年1月至2012年7月消化内分泌科明确诊断为DGP的患者75例,随机分为观察组(35例)和对照组(40例),观察组患者给予莫沙必利联合前列地尔治疗,对照组患者给予多潘立酮治疗,观察两组临床症状疗效,比较随访3、6个月的复发率。结果治疗后观察组总有效率[88.57%(31/35)]高于对照组[67.50(27/40)],3、6个月复发率均低于对照组,差异均有统计学意义(P<0.05)。结论莫沙必利联合前列地尔是DGP治疗的有效方法,值得临床应用。
Objective To explore the the curative effect of mosapride combined with alprostadil in treating diabetic gas troparesis（DGP）. Methods A total of 75 diagnosed DGP patients in digestive and endocrine department in the hospital from January 2009 to July 2012 were selected and randomized into observation group（n=35） and control group（n=40）,the observation group was given mosapride combined with alprostadil,while the control group was with domperidone for treatment. The clinical ef-ficacy and recurrence rate after 3,6 months follow-up in the two groups were observed and compared. Results After treatment, the total effective rate in the treatment group [88.57%（31/35）] was higher than that in the control group[67.50%（27/40）],and the occurrence rate after 3,6 follow-up in the treatment group were both lower than those in the control group,and the difference all had statistical significance（P〈0.05）. Conclusion Mosapride combined with alprostadil is effective for DGP,and it is worthy of clinical promotion.
出处
《现代医药卫生》
2014年第22期3393-3394,共2页
Journal of Modern Medicine & Health
关键词
糖尿病
胃肌轻瘫
胃排空
多潘立酮
前列地尔
治疗结果
莫沙必利
Diabetes mellitus
Gastroparesis
Gastric emptying
Domperidone
Alprostadil
Treatment out-come
Mosapride
