摘要
目的探讨慢性肾功能不全终末期血液透析患者使用静脉注射铁剂及口服铁剂治疗肾性贫血的临床疗效。方法将我院60例接受血液透析治疗的尿毒症伴有肾性贫血患者在应用重组人红细胞生成素(rHuEPO)治疗的基础上随机分为实验组和对照组,实验组患者应用静脉注射途径补充铁剂治疗,对照组患者口服途径补充铁剂治疗,比较两组患者治疗前、治疗8周后血红蛋白(Hb)、红细胞压积(Hct)、血清铁蛋白(SF)、转铁蛋白饱和度(TSAT)各项指标变化。结果治疗后两组患者Hb、Hct、SF、TSAT水平均显著升高(P<0.05),且观察组患者贫血改善程度及体内铁蛋白及转铁蛋白饱和度升高更加明显,差异有统计学意义。结论静脉补充铁剂较口服补充铁剂能更好、更快改善慢性肾功能不全患者的肾性贫血症状。
Objective To compare the clinical efficacy of iron sucrose injection vs ferrous succinate tablets in the treatment of renal anemia in maintenance hemodialysis. Mehtods forty cases of maintenance hemodialysis were randomly divided into introwenous iron supplementation group and oral iron supplementation group. before and2. 4 weeks after iron supplementation,hemoglobin（ Hb） hematocrit（ Hct） serum ferritin（ SF） and transferrin saturation（ TSAT） were examined. Ressult After treatment Hb Hct SF and TSAT were significantly increased in both groups,more significantly in intravenous iron supplementation group than in oral supplementation group. Conclutions In the combined use of recombinant hunman erythropoietin,intravenous iron supplementation can improve renal anemia more quickly and effectively than oral iron supplementation.
出处
《内蒙古医学杂志》
2014年第9期1057-1059,共3页
Inner Mongolia Medical Journal
关键词
铁剂
尿毒症
肾性贫血
ferralia
uremia
renal anemia。
