摘要
目的 调查任丘市老年城乡居民颈动脉粥样硬化（CAS）患病情况,分析其危险因素.方法 随机整群抽样法选择任丘市常住居民5010例,男性2163例,女性2847例,进行面对面健康问卷调查、体格检查、实验室检测和颈部血管超声检查.CAS包括颈动脉狭窄和斑块形成.分析CAS的危险因素.结果 5010例调查者中,颈动脉正常567例,内膜中层厚度增厚1 671例,颈动脉斑块形成2490例,颈动脉狭窄282例.CAS多因素logistic回归分析提示：校正混杂因素后,男性（OR=3.405,95％CI：2.704-4.289,P＜0.01）、年龄（OR=1.142,95％CI：1.103-1.181,P＜0.01）、脑卒中或短暂性脑缺血发作（OR=1.910,95％CI：1.342-2.718,P＜0.01）、吸烟（OR=1.799;95％CI：1.429-2.264;P＜0.01）、使用抗血小板药物（OR=1.313,95％CI：1.068-1.615,P＜0.05）、收缩压（OR=1.011,95％CI：1.007-1.015,P＜0.01）、空腹血糖（OR=1.151,95％CI：1.062-1.248,P＜0.01）、LDL-C（OR=2.038,95％CI：1.764-2.354,P＜0.01）、HDL-C（OR=0.787,95％CI：0.638-0.971,P＜0.05）为CAS的独立危险因素.结论 任丘市60-70岁人群CAS的患病率高,收缩压、血糖、LDL-C、吸烟是CAS重要的可干预的危险因素,有效控制血压、血糖、血脂,积极推进戒烟运动,延缓CAS病变,可进一步减少心脑血管病的发生.
Objective To investigate the prevalence of carotid atherosclerosis （CAS） in Renqiu elderly residents of Hebei Province and analyze its risk factors.Methods The prevalence of CAS （carotid stenosis and plaques） in 5010 permanent Renqiu residents （2163 males and 2847 females） selected by random cluster sampling was investigated with health questionnaires,and by laboratory test,anthropometry and neck vascular ultrasonography.The risk factors for CAS were analyzed by multivariate logistic regression analysis.Results The carotid artery was normal in 567,carotid IMT was thickened in 1671,formation of carotid plaques was detected in 2490,and carotid stenosis was observed in 282 out of the 5010 permanent Renqiu residents.Multivariate logistic regression analysis showed that after adjustment for confounding factors,male gender,age,history of is chemic stroke or TIA,smoking,use of antiplatelet drugs,systolic blood pressure,elevated fasting blood glucose and LDL-C level and decreased HDL C level were the independent risk factors for CAS （P＜0.05,P＜0.01）.Conclusion The prevalence of CAS is high in 60-70 years old Renqiu residends.Systolic blood pressure,fasting blood glucose and LDL-C level,and smoking are the independent risk factors for CAS.Effective control of blood pressure,blood glucose and blood lipid,and giving up smoking can delay the development of CAS and further reduce the occurrence of cardio-cerebrovascular diseases.
出处
《中华老年心脑血管病杂志》
CAS
北大核心
2014年第11期1127-1132,共6页
Chinese Journal of Geriatric Heart,Brain and Vessel Diseases
关键词
颈动脉疾病
糖尿病
血脂异常
高血压
危险因素
carotid artery diseases
diabetes mellitus
dyslipidemias
hypertension
risk factors
