摘要
目的:探讨中药康复新液对肛瘘术后创面愈合临床效果观察及安全性评价,为临床诊断治疗提供参考。方法:将本组130例肛瘘患者根据随机数字表法随机治疗组(n=65)和对照组(n=65)。治疗组给予中药康复新液治疗;对照组给予高锰酸钾溶液治疗。对比分析两组患者治疗后临床疗效,术后第1、3、5、7及第14 d疼痛评分和创面面积及创面愈合时间和住院时间。结果:治疗组治疗后总有效率(95.83%)显著高于对照组(81.54%),且有显著性差异;治疗组术后第3、5、7 d VAS评分均显著低于对照组,且有显著性差异(P<0.05);治疗组术后第7、14 d创面面积显著少于对照组,且有显著性差异(P<0.05);治疗组治疗后创面愈合时间及住院时间均明显短于对照组,且有显著性差异(P<0.05);两组治疗后均未出现明显不良反应。结论:中药康复新液对肛瘘术后创面愈合具有明显的临床效果,缩短其创面愈合时间,降低疼痛,无明显不良反应,安全可靠,具有重要的临床研究价值,值得推广应用。
Objective ： To investigate the clinical effect and safety evaluation of Kangfuxin liquid on anal fistula healing and to provide a reference for clinical diagnosis and treatment. Methods ： 130 cases of fistula patients based on a random number table were randomized into treatment group （ n = 65） and control group （ n = 65 ）. The treatment group received a new liquid medicine rehabilitation therapy and the control group was given potassium permanganate solution. Comparative analysis of the clinical efficacy of two groups of patients 1 d, 3 d,5 d, 7 d and 14 d after operation, the pain score, the wound area,wound healing time and hospital stay were carried out. Results： After treatment, the treatment group＇ s total efficiency （95.83%） was significantly higher than that of control group （81.54%） and there was a significant difference. In treatment group 3 d,5 d,7 d after operation, VAS scores were significantly lower than that of the control group and there was a significant difference （P 〈 0.05 ）. In treatment group 7 d and 14 d after operation, the first wound area was significantly less than that of the control group and there was a significant difference （ P 〈 0.05 ）. After treatment, healing time and hospital stay were significantly shorter than those of the control group and there was a significant difference （P 〈 0.05 ）. There was no obvious adverse reaction after treatment. Conclusion： Kangfuxin liquid on anal fistula healing has obvious clinical effect. It can shorten healing time and reduce pain with no significant adverse reactions. It is safe and reliable and has important clinical research value. It should be widely applied .
出处
《中华中医药学刊》
CAS
2014年第11期2809-2811,共3页
Chinese Archives of Traditional Chinese Medicine
关键词
康复新液
肛瘘
创面愈合
效果
安全性
rehabilitation new liquid
anal fistula
wound healing
effect
safety
