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胃癌原发灶和区域淋巴结转移灶中ZNF139与MRP-1、MDR1/P-gp、GST-π的表达及关系

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摘要 本研究通过分析胃癌区域淋巴结转移灶与原发灶锌指蛋白139(zinc finger protein 139,ZNF139)、多药耐药相关蛋白-1 (multidrug resistance associated protein-1,MRP-1)、多药耐药基因1/P-糖蛋白(multidrug resistance gene 1/P-glycoprotein,MDR1/P-gp)、谷胱甘肽转移酶-π(glutathione-transferase-π,GST-π)的表达及其关系,为阐明ZNF139与胃癌多药耐药性(multidrug resistance,MDR)的关系提供依据.
出处 《中华普通外科杂志》 CSCD 北大核心 2014年第10期801-802,共2页 Chinese Journal of General Surgery
基金 国家自然科学基金资助项目(81072033、81372580) 河北省自然科学基金资助项目(C2010000619) 河北省普通高校强势特色学科资助项目(冀教高[2005] 52) 河北省卫生厅科研基金资助项目(20110460)
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参考文献3

  • 1Li Y, Tan BB, Fan I,Q, el al. tlcterogeneity flr COX-2, multidrugs resistance between primaU tumors and regional lymph node metastases of gastric cancer[ J ]. Tumori, 2012, 98 (4) : 516-522.
  • 2Li Y, Tan BB, Zhao Q, ctal. Hegulalory mechanism of ZNF139 in muhi-drug resistance of gastric cancer cells [J]. Mol Biol Rep, 2014, 41 (6) :3603-3610.
  • 3宋延强,李扬,林惠忠,庞新建,李林浩.胃癌新辅助化疗前后多药耐药基因的表达及其与化疗敏感性的关系[J].中华普通外科杂志,2009,24(5):365-367. 被引量:5

二级参考文献9

  • 1李亦蕾,吴曙光.洛拉曲克对胸苷酸合成酶蛋白质表达水平的动态影响[J].第一军医大学学报,2004,24(8):881-884. 被引量:2
  • 2帅晓明,韩高雄,陈俊华,王国斌.胃癌体外药敏试验与多药耐药基因、多药耐药相关蛋白表达的关系[J].中华实验外科杂志,2006,23(10):1218-1220. 被引量:9
  • 3Ji JF,Yu Z,Zhang XN,et al.Oxanliplant-based regimen as neoadjuvant chemotherapy for Chinese patient with advanced gastric:preliminary result of aphase Ⅱ study.Proc Am Soc Clin Oncol,2004,4184.
  • 4Nakajima T,Kinoshita T,Nashimoto A,et al.Randomized controlled trial of adjuvant uracil-tegafur versus surgery alone for serosa-negative,locally advanced gastric cancer.Br J Surg,2007,94:1468-1476.
  • 5Sakuramoto S,Sasako M,Yamaguchi T,et al.Adjuvant chemotherapy for gastric cancer with S-1,an oral fluoropyrimidine.N Engl J Med,2007,357:1810-1820.
  • 6Nitti D,Wils J,Dos Santos JG,et al.Randomized phase Ⅲ trials of adjuvant FAMTX or FEMTX compared with surgery alone in resected gastric cancer:a combined analysis of the EORTC GI Group and the ICCG.Ann Oncol,2006,17:262-269.
  • 7Cascinu S,Labianca R,Barone C,et al.Adjuvant treatment of high-risk,radically rosected gastric cancer patients with 5-fluorouracil,leucovorin,eisplatin,and epidoxorubicin in a randomized controlled triM.J Natl Cancer Inst,2007,99:601-607.
  • 8Fukuda H,Takiguchi N,Koch K,et al.Thymidylate synthase and dihydropyrimidine dehydrogenase are related to histological effects of 5-fluorouracil and cisplatin neoadjuvant chemotherapy for primary gastric cancer patients.Cancer Invest,2006,24:235-241.
  • 9Ott K,Weber WA,Lordick F,et al.Metabolic imaging predicts response,survival,and recurrence in adenocarcinomas of the esophagogastric junction.J Clin Oncol,2006,24:4692-4698.

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