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New strategies for the repair of spinal cord injury 被引量:1

New strategies for the repair of spinal cord injury
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摘要 Spinal cord injury(SCI)leads to several neurologic damages to patients with sensory and motor function loss.Although some inspiring results were reported in animal,even in non-human primate models,the clinical translation of these research achievements barely move forward for the SCI patients.This review mainly focused on the pathogenesis of the primary and secondary injury,the clinical therapies and the new technologies in spinal cord injury.Moreover,the key scientific issues on this field were discussed in the review.Finally,some suggestions were proposed for the scientific and clinical researches. Spinal cord injury (SCI) leads to several neu- rologic damages to patients with sensory and motor func- tion loss. Although some inspiring results were reported in animal, even in non-human primate models, the clinical translation of these research achievements barely move forward for the SCI patients. This review mainly focused on the pathogenesis of the primary and secondary injury, the clinical therapies and the new technologies in spinal cord injury. Moreover, the key scientific issues on this field were discussed in the review. Finally, some suggestions were proposed for the scientific and clinical researches.
出处 《Chinese Science Bulletin》 SCIE EI CAS 2014年第31期4041-4049,共9页
基金 supported by the Basic Programof National Natural Science Foundation of China(81330030) the Young Scholar Program of National Natural Science Foundation of China(81301042) the Program of Shanghai Subject Chief Scientist(2012XD1404400)
关键词 脊髓损伤 修复 临床治疗 动物模型 科学问题 运动功能 研究成果 发病机制 Spinal cord injury Secondary injury Repair Regeneration Stem cells
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