摘要
多索茶碱是新一代甲基黄嘌呤的衍生物,主要用于支气管痉挛引起的呼吸困难。本品属于茶碱、氨茶碱替代品,比传统的药物茶碱和氨茶碱疗效高且毒性低。通过大量多索茶碱相关文献,从基本情况、作用机制、药理作用、临床应用及有关物质及含量对多索茶碱进行了总结,对多索茶碱的研究提供了有益借鉴,对多索茶碱注射液有关物质和含量方法学验证奠定基础。
Doxofylline is the new generation methyl xanthine derivativ, which canbe applied to dyspnea caused by bronchospasm. Doxofylline is a substitute for traditional theophylline and aminophylline, and is much moreeffective but less toxic. From many related literatures on doxofylline,this article not only sμmmarizes its general situation, mechanism of action, pharmacological action,clinical application and related substances and their contents,but also provides many references onthe researchof doxofylline,and hence lays a foundation on determination of the content and the related substances of it.
出处
《中国医药指南》
2014年第28期78-79,共2页
Guide of China Medicine
关键词
多索茶碱
药理作用
临床评价
色谱条件
Doxofylline injection
Pharmacological effect
Clinical Evaluation
Chromatographic condition
